Fulminant hepatic failure secondary to amebic abscesses |
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Authors: | Dr David A Saltzman MD Neil Smithline MD John R Davis MD |
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Institution: | (1) Sections of Gastroenterology and Renal Disease, Department of Internal Medicine, University of Arizona School of Medicine, 85724 Tucson, Arizona;(2) Department of Pathology, University of Arizona School of Medicine, 85724 Tueson, Arizona |
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Abstract: | Summary A patient presented with fulminant hepatic failure which rapidly led to his death. At postmortem examination, he had several amebic abscesses secondarily infected with bacteria, one of which had ruptured intraperitoneally, and another of which had occluded major hepatic veins of the right lobe of the liver. In addition, pylephlebitis and occlusion of several right portal venous radicies were noted. Microscopic examination of the right lobe revealed marked sinusoidal congestion and large areas of infarction with severe panlobular necrosis. Fuiminant hepatic failure secondary to complications of amebic abscess has been reported infrequently but should be considered in patients with this presentation who have visited or inhabited areas endemic for amebiasis. |
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