Fixation of osteotomies of the distal femur with absorbable, self-reinforced, poly-L-lactide plates |
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Authors: | K. Koskikare E. Hirvensalo H. Pätiälä P. Rokkanen T. Pohjonen P. Törmälä G. Lob |
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Affiliation: | (1) Helsinki University Central Hospital, Topeliuksenkatu 5, FIN-00260 Helsinki, Finland;(2) Biomaterials Laboratory, Tampere University of Technology, Tampere, Finland;(3) Chirurgische Klinik der Ludwik-Maximilians-Universität, Klinikum Grosshadern, Marchionistrasse 15, München, Germany |
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Abstract: | Osteotomies of the distal femur were fixed with two self-reinforced poly-L-lactic acid (SR-PLLA) plates and metallic screws placed through the plates on each side of the femur in 23 adult rabbits. They were followed-up after 3, 6, 12 and 24 weeks. After killing, radiological, histological, microradiographic and oxytetracycline fluorescence studies were performed. Except for one histologically confirmed fibrotic non-union at 24 weeks, the osteotomies healed, including one involving a rabbit which had suffered an ipsilateral femoral shaft fracture of unknown cause. No malformations were observed, and the macroscopically detected swelling was a normal postoperative reaction. This study showed that SR-PLLA plates implanted on both sides on the bone are suitable for the fixation of weight-bearing cancellous bone osteotomies in rabbits. |
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