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正交设计优选前列保颗粒水提工艺
引用本文:兰星,夏新华,朱青,杜帆.正交设计优选前列保颗粒水提工艺[J].中国中医药信息杂志,2012,19(5):58-60.
作者姓名:兰星  夏新华  朱青  杜帆
作者单位:湖南中医药大学药学院,湖南,长沙,410208
摘    要:目的优选前列保颗粒最佳水提工艺条件。方法以浸膏得率、马钱苷含量为评价指标,以浸泡时间、加水量、提取时间为考察因素,采用正交试验法对前列保颗粒的水提取工艺进行优选。结果最佳水提取工艺为:加水浸泡1.5 h,提取2次,加水量分别为8、6倍量,提取时间分别为2.0、1.5 h。结论优选的工艺合理可行,适用于工业大生产。

关 键 词:前列保颗粒  水提工艺  正交试验  马钱苷

Optimization of Water Extraction Process of Qianliebao Granules by Orthogonal Tests
LAN Xing , XIA Xin-hua , ZHU Qing , DU Fan.Optimization of Water Extraction Process of Qianliebao Granules by Orthogonal Tests[J].Chinese Journal of Information on Traditional Chinese Medicine,2012,19(5):58-60.
Authors:LAN Xing  XIA Xin-hua  ZHU Qing  DU Fan
Institution:(School of Pharmacy,Hunan University of TCM,Changsha 410208,China)
Abstract:Objective To optimize the water extraction conditions of Qianliebao Granules.Methods The extraction conditions were optimized by orthogonal tests with the extract yield and the amount of the extracted loganin as indexes,and soaking time,water volume and extracting time as factors.Results The optimum extraction process was as follows:soaking in water for 1.5 h,decocting 2 times,adding water for 8,6 times and extracting for 2.0,1.5 h,respectively.Conclusion The optimum extraction process is reasonable,feasible,and suitable for industrialized production.
Keywords:Qianliebao Granules  extraction process  orthogonal tests  loganin
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