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痛经舒巴布膏制备工艺的研究
引用本文:庄桂霞,赵晓霞,杨晓宁,胥云. 痛经舒巴布膏制备工艺的研究[J]. 中国中药杂志, 2005, 30(11): 824-826
作者姓名:庄桂霞  赵晓霞  杨晓宁  胥云
作者单位:中国医药研究开发中心有限公司,北京,102206
摘    要:目的:确立痛经舒巴布膏最佳制备工艺.方法:以剥离强度、内聚力为量化指标,采用L9(34)正交试验优选基质,同时对最佳含水量进行单因素考察.结果:最佳工艺由浸膏:聚丙烯酸钠:甘油:粘合剂为0.2:4:8:1.2的比例,膏体含水为35%时粘贴性能好,剥离无残留,皮肤无刺激、无过敏现象.结论:痛经舒巴布膏配方合理,制备简单易行.

关 键 词:痛经舒巴布膏  制备工艺  正交试验  含水量
文章编号:1001-5302(2005)11-0824-03
收稿时间:2005-01-28

Experimental studies on the preparation techniques of Tongjingshu babu sticking plaster
ZHUANG Gui-xia;ZHAO Xiao-xia;YANG Xiao-ning;XU Yun. Experimental studies on the preparation techniques of Tongjingshu babu sticking plaster[J]. China Journal of Chinese Materia Medica, 2005, 30(11): 824-826
Authors:ZHUANG Gui-xia  ZHAO Xiao-xia  YANG Xiao-ning  XU Yun
Affiliation:National Institute of Pharmaceutical Development and Research Co. Ltd., Beijing 102206, China. lily@58@163.com
Abstract:Objective: to establish the optimum preparation procedure for Tongjingshu babu sticking plaster. Method: Orthogonal design was used to observe the adhesion power, cohesion by the multi-electronic experimental equipment. Result: The best formulation is composed of ointment, polypropylene acid, glycerin, bond and its proportion is 0.2:4:8:1.2, the final plaster contains 35 % water with idea stability to the skin. Conclusion: The formulation of Tongjing-shu babu sticking plaster is resonable and its preparation is simple and rapid.
Keywords:Tongjing-shu babu sticking plaster  preparation techniques  orthogonal design  water content  
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