On the resorption of parenterally administered saline solutions in experimental shock

Summary Parenteral administration of medicinal preparations during shock should be based on the knowledge of the resorption rate of medicinal substances in the tissues during various phases of shock. In this connection the resorption of Na²⁴Cl and Na₂HP³²O₄ was studied after intramuscular, subcutaneous and intradermal injections. The rate of the resorption was assessed by the time required for semi-elimination of Na²⁴ from the site of its administration, and for the appearance of the maximal P³² concentration in the circulating blood.As established, the rate of resorption of parenterally administered microdispersed substances in experimental shock decreases. This delayed resorption is determined by the phase of shock and becomes greater with the increased severity of the latter.(Presented by Active Member AMN SSSR S. V. Anichkov) Translated from Byulleten Eksperimental'noi Biologii i Meditsiny, Vol. 51, No. 2, pp. 21–23, February, 1961