胸腔镜应用在肺癌手术患者感染预防中的综合效果观察

目的比较电视胸腔镜手术与传统开胸手术的急性期反应程度,探讨胸腔镜应用在肺癌手术感染中的预防作用。方法将65例肺癌患者分为胸腔镜手术组(VATS组)35例和传统开胸手术组(CTH组)30例,统计术后两组感染病例,并检测手术前、手术后第1、3天的白细胞介素-6(IL-6)和CRP浓度。结果 VATS组肺部感染1例,切口感染0例,CTH组肺部感染8例,切口感染4例,经过有效引流,选用敏感抗菌药物,加强支持疗法治愈;术前VATS组IL-6和CRP浓度分别为(27.58±3.30)pg/ml、(7.29±3.24)mg/L,CTH组为(30.40±4.25)pg/ml、(7.38±3.46)mg/L;术后第1、3天VATS组IL-6浓度分别为(83.15±18.91)、(55.49±9.87)pg/ml,CTH组为(117.55±23.34)、(74.14±13.71)pg/ml;术后第1、3天VATS组CRP浓度分别为(67.43±10.27)、(48.83±16.28)mg/L,CTH组为(98.72±11.73)(、65.23±19.81)mg/L,两组术前IL-6和CRP的浓度均差异无统计学意义;而在术后第1、3天血清IL-6和CRP浓度VATS组均低于CTH组,差异有统计学意义。结论胸腔镜手术较传统的开胸手术创伤小,术后炎症迅速减轻,从而有效预防术后感染。

Combined effect of video-assisted thoracoscopic surgery applied in infection prevention for lung cancer patients

OBJECTIVE To compare the acute inflammatore reactions after video-assisted thoracoscopic surgery(VATS) and conventional thoracotomy(CTH),application of thoracoscopy in lung cancer surgery in the prevention of infection.METHODS A total of 65 patients with lung cancer were randomly assigned to the VATS group(n=35) and the conventional thoracotomy group(n=30).Serum IL-6 and C-reactive protein(CRP) were detected respectively before operation,at 1 day after operation,and at 3 days after operation.RESULTS In VATS...