452例缺血性脑血管疾病DSA分析

目的探讨缺血性脑血管病患者脑动脉狭窄或闭塞的分布特征,为脑血管病防治提供参考。方法 452例缺血性脑血管病患者的DSA资料,按年龄大小分为青年组、中年组和老年组。结果 452例经DSA检查确诊为动脉粥样硬化性狭窄或闭塞,其中,35.2%仅有颅内病变,31.8%仅有颅外病变,33.0%颅内、外病变并存;颅内病变的发生率为68.1%,稍高于颅外病变的64.8%。青年组单纯颅内病变的比例较高（75.0%）;中年组（38.5%）低于青年组（P〈0.01）;老年组（28.1%）低于中年组（P〈0.05）;老年组以颅内外病变并存的比例较高（36.8%,P〈0.01）。后循环病变老年组高于中年组（P〈0.05）,中年组高于青年组（P〈0.01）。危险因素中高血压、吸烟、糖尿病、血脂异常、脑卒中史、脑血管病家族史,在颅内、颅外及颅内外病变并存的患者间比较差异无统计学意义,高龄在颅外及颅内外动脉病变并存中的比例明显高于在颅内动脉病变中的比例（P〈0.01）。结论缺血性脑血管病患者中,颅内动脉粥样硬化性病变的发生率高于颅外段,随着年龄的增长,颅外动脉病变及颅内外动脉病变并存的比例逐渐增多,后循环病变增多。高龄是颅外动脉病变的显著性危险因素。

Analysis of DSA in 452 cases of ischemic cerebrovascular disease

Objective To investigate distribution characteristics of ischemic cerebrovascular disease brain artery stenosis or block,to provide reference for cerebrovascular disease prevention and treatment.Methods The DSA of 452 patients with ischemic cerebrovascular disease was investigated.According to age,the patients were divided into young-aged group,middle-aged group and old-aged group.Results Four hundred and fifty-two cases were diagnosed of cerebral atherosclerotic artery stenosis or occlusion,among whom 35.2% had only intracranial disease,31.8% had only extracranial artery disease,and 33.0% had both intracranial and extracranial arterial disease.The incidence of intracranial lesions for 68.1% little more than 64.8% of extracranial lesions.The proportion of pure youth intracranial lesions higher (75.0%);Middle age group (38.5%) was lower than the young group (P< 0.01);The elderly group (28.1%) was lower than the middle age group (P< 0.05);Old outside the coexistence of intracranial lesions in the higher percentage (36.8%,P< 0.01).The posterior circulation lesions old was higher than the middle-aged group (P< 0.05),middle age group was higher than the young group (P< 0.01).Risk factors of high blood pressure,smoking,diabetes,dyslipidemia,stroke history,cerebrovascular disease,family history,in the intracranial,extracranial and intracranial lesions of the coexistence between patients with comparative differences had no sense of statistics,in the age of cranial and intracranial arteries in proportion to the coexistence was obviously higher than intracranial arteries in the proportion (P< 0.01).Conclusion The morbidity of intracranial arterial disease is higher than that of extracranial artery disease in ischemic cerebrovascular disease,the distribution of cerebral artery disease varies with age,the proportion of extracranial artery disease and co-existence of craniocervical artery disease gradually increased with age and posterior circulation lesions gradually increased in the same way.Seniority is a significant risk factor in extracranial artery disease.