Hepatoportal sclerosis clinical different evolutionary stages: presentation of 3 cases and literature review |
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Authors: | Martínez-Caselles Alejandro Pons-Mi?ano José Antonio Vargas-Acosta ángel Ortiz-Sánchez María Luisa Martínez-Pascual Cristina Ruiz-Maciá José Antonio Ferri Belén Ortiz-Ruiz Eduardo Sola Joaquín |
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Institution: | Department of Digestive Diseases, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain. alexmart82@hotmail.com |
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Abstract: | Hepatoportal sclerosis (HPS) is characterized by presinusoidal intrahepatic portal hypertension associated with splenomegaly and anemia in patients with non-cirrhotic liver. Liver biopsy is essential, especially to rule out other processes. Being a disease of unknown etiology, the majority of cases have been described in eastern countries. However, it may be an underdiagnosed disease in the West. Symptoms are related to portal hypertension and the clinical spectrum is wide, ranging from anemia with normal liver function tests to bleeding due to esophageal varices. Treatment is directed to the complications and the prognosis is better than in patients with cirrhosis.We report three cases of HPS presenting at different clinical stages and the findings of liver biopsies, the clinical outcomes and a review of scientific literature. |
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