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经颅超声溶栓联合巴曲酶治疗基底动脉尖综合征临床研究
引用本文:李文波,马聪敏,魏立平,张宏伟. 经颅超声溶栓联合巴曲酶治疗基底动脉尖综合征临床研究[J]. 中国实用神经疾病杂志, 2009, 12(1)
作者姓名:李文波  马聪敏  魏立平  张宏伟
作者单位:河南洛阳市中心医院神经内科,洛阳,471000
摘    要:目的 评价经颅超声溶栓联合巴曲酶治疗基底动脉尖综合征的临床效果.方法 对19例经MRI证实为基底动脉尖综合征的病人,巴曲酶首次应用剂量为10BU,另两次为5BU,隔日1次,共3次.使用前用250ml生理盐水稀释,静滴1h以上,应用超声溶栓治疗仪(频率800kHz,0.75W/cm.脉冲超声)治疗,2次/d,20min/次,共21d.对治疗前后的疗效进行评定.结果 治疗后3周,用NIH-NINDS中风评分量表评分,经颅超声加巴曲酶治疗前得分9.33±1.46,治疗后7.67±1.89,即经颅超声加巴曲酶治疗对神经功能恢复的效果最显著,治疗过程中未见不良反应.结论 巴曲酶联合经颅超声溶栓治疗基底动脉尖综合征是一种安全有效的方法 ,值得临床推广应用.

关 键 词:经颅超声溶栓  巴曲酶  基底动脉尖综合征

Clinical study of transcranial ultrasound plus batroxobin thrombolysis in the treatment of patients with top of the basilar syndrome
Li Wenbo,Ma Congmin,Wei Liping,et al.. Clinical study of transcranial ultrasound plus batroxobin thrombolysis in the treatment of patients with top of the basilar syndrome[J]. Chinese Journal of Practical Neruous Diseases, 2009, 12(1)
Authors:Li Wenbo  Ma Congmin  Wei Liping  et al.
Affiliation:Li Wenbo,Ma Congmin,Wei Liping,et al.Department of Neurology,Luoyang Cental Hospital,Louyang 471009,China
Abstract:Objective To study the clinical outcome of transcranial ultrasound plus batroxobin thrombolysis in the treatment of patients with top of the basilar syndrome.Methods Nineteen patients in the treatment of transcranial ultrasound plus batroxobin thrombolysis were confirmed with top of the basilar syndrome by MRI.A dose of batroxobin 10BU dissolved in normal saline 250ml was given by intravenous infusion about 1 hour at first,the other times was 5BU every two days,the totle was three times.Ultrasound(800kHz,0....
Keywords:Transcranial ultrasound  Batroxobin thrombolysis  Top of the basilar syndrome  
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