| 树突状细胞肿瘤疫苗用于胃癌免疫治疗的新进展 |
| |
| 引用本文： | 宁敏曼,王立. 树突状细胞肿瘤疫苗用于胃癌免疫治疗的新进展[J]. 医学综述, 2006, 12(4): 200-202 |
| |
| 作者姓名： | 宁敏曼 王立 |
| |
| 作者单位： | 重庆医科大学附属第一医院消化内科,重庆,410006 |
| |
| 摘 要： | 树突状细胞(DCs)即是体内最有效的专业抗原提呈细胞,也是抗原特异性免疫应答的始动者,具有摄取、加工、递呈抗原至T淋巴细胞的能力,表达高水平的MHCⅠ、Ⅱ和CD80、CD86等共刺激分子,在免疫应答中起关键作用。以DCs为基础的各种疫苗在胃癌免疫治疗中取得了很大的成就。
|
| 关 键 词： | 胃肿瘤 树突状细胞 免疫治疗 |
| 文章编号： | 1006-2084（2006）04-0200-03 |
| 收稿时间： | 2005-07-13 |
| 修稿时间： | 2005-12-04 |
The Progress about Immunotherapy of Gastric Carcinoma Using Dendritic Cell Tumor Vaccines |
| |
| NING Min-man,WANG Li. The Progress about Immunotherapy of Gastric Carcinoma Using Dendritic Cell Tumor Vaccines[J]. Medical Recapitulate, 2006, 12(4): 200-202 |
| |
| Authors: | NING Min-man WANG Li |
| |
| Affiliation: | The Department of Digestive Disease of the First Affiliated Hospital of Chongqing Medical University, Chongqing 410006, China |
| |
| Abstract: | Dendritic cells are not only the most effective and professional antigen-presenting cells,but also the initiator of antigen-specific immune responses.They can capture,process and present antigens to T lymphocyte and highly express MHC-Ⅰ,MHC-Ⅱ and many other costimulatory molecules such as CD_(80)、CD_(86) and so on.Dendritic cells play a key role in immune responses.Moreover,various vaccines based on DC-achieved a significant success in gastric cancer immunotherapy. |
| |
| Keywords: | Stomach neoplasms Dendritic cells Immunotherapy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
