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盐酸奥昔麻黄碱治疗冠心病心绞痛的临床疗效
引用本文:徐济民,黄震华.盐酸奥昔麻黄碱治疗冠心病心绞痛的临床疗效[J].中国新药与临床杂志,1989(3).
作者姓名:徐济民  黄震华
作者单位:上海第二医科大学附属第九人民医院内科,上海第二医科大学附属第九人民医院内科 上海 200011,上海 200011
摘    要:本文应用盐酸奥昔麻黄碱治疗110例冠心病心绞痛患者,用法:wk1给安慰剂,wk2,3口服奥昔麻黄碱,8mg,tid,wk4,5给安慰剂。结果:奥昔麻黄碱组症状疗效为88.2%,安慰剂组为35.4%(P<0.01),奥昔麻黄碱组心电图疗效为51.8%。本药并可使收缩时间间期(STI)缩短,心率加快,副作用小,可作为治疗冠心病心绞痛有效药物之一。

关 键 词:奥昔麻黄碱  心绞痛  冠状动脉疾病

Advantages of oxyfedrine hydrochloride in the management of coronary heart disease with angina pectoris in clinic
XU Ji-Min,HUANG Zhen-Hua.Advantages of oxyfedrine hydrochloride in the management of coronary heart disease with angina pectoris in clinic[J].Chinese Journal of New Drugs and Clinical Remedies,1989(3).
Authors:XU Ji-Min  HUANG Zhen-Hua
Abstract:110 patients suffered from coronary heart disease with angina pectoris were treated with oxyfedrine hydrochloride. Results proved that this therapy is quite promising .Placebo was given on the 1st, 4th and 5th week while oxyfedrine hydrochloride 8 mg tid on the 2nd and 3rd week.Improvements following the treatment were found to be 88.2% while the placebo 35.4% only(P<0.001) .Correspondingly ECG returned almost to normal in 51.8%.At the mean time the systolic time interval was shortened and heart rate increased. Adverse effects were rare.
Keywords:oxyfedrine  angina pectoris  coronary disease
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