Goodpasture's syndrome |
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Authors: | Shinjo Samuel Katsuyuki Hasegawa Eduardo Massato Costa Malheiros Denise Maria Avancini Levy-Neto Mauricio |
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Affiliation: | Disciplina da Reumatologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de S?o Paulo, S?o Paulo, Brasil. samuel.shinjo@gmail.com |
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Abstract: | Goodpasture s syndrome (GS) is an auto-immune disease that is part of the pulmonary-renal syndrome spectrum. It is characterized by the linear deposition of anti-glomerular basement membrane antibodies (anti-GBM) in glomerular and alveolar basement membrane resulting in alveolar hemorrhage and progressive glomerulonephritis. An early diagnosis is important to decrease clinical morbidity. In the present work we illustrate a GS case initially diagnosed as Wegener s granulomatosis. The patient showed favorable clinical evolution with corticosteroid therapy associated with plasmapheresis and cyclophosphamide. |
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