老年2型糖尿病患者下肢血管病变相关因素分析

目的探讨老年2型糖尿病患者下肢血管病变相关因素。方法利用彩色多普勒超声诊断仪检查240例老年2型糖尿病患者,确定下肢血管病变。根据下肢血管病变程度将患者分为3组:无下肢血管病变组(27例);中度下肢血管病变组(154例);重度下肢血管病变组(59例)。同时观察和分析临床因素及生化指标与下肢血管病变之间的相关性。结果中度下肢血管病变组视网膜病变的患者发生下肢血管病变的比例高(P<0.05);重度下肢血管病变组病程>5年、有家族史、周围神经病变及视网膜病变的患者发生下肢血管病变的比例高。有下肢血管病变组血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)水平较无下肢血管病变组明显升高。在中度及重度下肢血管病变组中,多因素分析显示下肢血管病变与病程及LDL-C呈正相关。结论糖尿病病程及LDL-C水平与糖尿病下肢血管病变密切相关。

Analysis of Risk Factors of Peripheral Artery Disease in Elder Type 2 Diabetic Patients

Objective To analyze the risk factors of peripheral artery disease in elder diabetic patients. Methods 240 elder type 2 diabetic patients were enrolled. Patients were divided into three groups. 27 patients had not peripheral artery disease; 154 had moderate peripheral artery disease; 59 had severe peripheral artery diseases. The relationship between seventy of peripheral artery diseases judged by doppler ultrasonic and biochemical parameters was investigated. Results In the moderate peripheral artery disease group, peripheral artery diseases were correlated to the retinopathy. In the severe peripheral artery disease group, peripheral artery diseases were correlated to family history, TC, LDL-C, pathological changes of perpheral nerve and retinopathy. Conclusion Peripheral artery diseases in the elderly diabetic patients correlate with the course of DM and LDL-C.