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Longitudinal Changes in Neuromelanin MRI Signal in Parkinson's Disease: A Progression Marker |
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| Authors: | Rahul Gaurav MS Lydia Yahia-Cherif PhD Nadya Pyatigorskaya MD PhD Graziella Mangone MD PhD Emma Biondetti PhD Romain Valabrègue PhD Claire Ewenczyk MD PhD R Matthew Hutchison PhD Jesse M Cedarbaum MD Jean-Christophe Corvol MD PhD Marie Vidailhet MD PhD Stéphane Lehéricy MD PhD |
| Institution: | 1. Paris Brain Institute– ICM, Center for NeuroImaging Research – CENIR, Paris, France;2. Paris Brain Institute– ICM, Center for NeuroImaging Research – CENIR, Paris, France
ICM, Sorbonne University, UPMC Univ Paris 06, Inserm U1127, CNRS UMR, Paris, France;3. Paris Brain Institute– ICM, Center for NeuroImaging Research – CENIR, Paris, France ICM, Sorbonne University, UPMC Univ Paris 06, Inserm U1127, CNRS UMR, Paris, France ICM Team “Movement Investigations and Therapeutics” (MOV'IT), Paris, France Department of Neuroradiology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France;4. ICM, Sorbonne University, UPMC Univ Paris 06, Inserm U1127, CNRS UMR, Paris, France INSERM, Clinical Investigation Center for Neurosciences, Pitié-Salpêtrière Hospital, Paris, France;5. Paris Brain Institute– ICM, Center for NeuroImaging Research – CENIR, Paris, France ICM, Sorbonne University, UPMC Univ Paris 06, Inserm U1127, CNRS UMR, Paris, France ICM Team “Movement Investigations and Therapeutics” (MOV'IT), Paris, France;6. ICM, Sorbonne University, UPMC Univ Paris 06, Inserm U1127, CNRS UMR, Paris, France ICM Team “Movement Investigations and Therapeutics” (MOV'IT), Paris, France Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France;7. Biogen Inc., Cambridge, Massachusetts, USA;8. ICM, Sorbonne University, UPMC Univ Paris 06, Inserm U1127, CNRS UMR, Paris, France INSERM, Clinical Investigation Center for Neurosciences, Pitié-Salpêtrière Hospital, Paris, France Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France |
| Abstract: | |
| Keywords: | neuroimaging biomarker neurodegenerative disorders parkinsonism substantia nigra |