| 七氟烷对顺式阿曲库铵和罗库溴铵肌松作用的影响 |
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| 引用本文： | 李春莲,崔薇,于泳浩.七氟烷对顺式阿曲库铵和罗库溴铵肌松作用的影响[J].中国中西医结合外科杂志,2011,17(2):165-167. |
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| 作者姓名： | 李春莲 崔薇 于泳浩 |
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| 作者单位： | 天津医科大学总医院麻醉科,天津,300052 |
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| 摘 要： | 目的：比较七氟烷对顺式阿曲库铵和罗库溴铵肌松效应的影响。方法：择期手术患者240例,随机分为顺式阿曲库铵组（CIS120例）和罗库溴铵组（ROC120例）。两组患者再随机分为丙泊酚组（60例）和七氟烷组（60例）,均静脉注射咪达唑仑、芬太尼和丙泊酚行麻醉诱导,丙泊酚组靶控输注丙泊酚维持麻醉,设定血浆靶控浓度2～6μg/mL,输注丙泊酚5min后静脉注射顺式阿曲库铵0.15mg/kg或罗库溴铵0.6mg/kg;七氟烷组在呼气末七氟烷浓度稳定于1MAC5min后静脉注射顺式阿曲库铵0.15mg/kg或罗库溴铵0.6mg/kg。结果：CIS两组,起效时间差异无统计学意义（P〉0.05）;七氟烷组完全肌松时间、维持时间与丙泊酚组比较均显著延长（P〈0.01）。ROC两组,起效时间差异无统计学意义（P〉0.05）;七氟烷组完全肌松时间、维持时间与丙泊酚组比较均显著延长（P〈0.01）。结论：七氟烷对顺式阿曲库铵及罗库溴铵的肌松均有增效作用。
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| 关 键 词： | 顺式阿曲库铵 罗库溴铵 神经肌肉阻滞 七氟烷 |
Comparison of effect of Sevoflurane on Neuromuscular Blockade Induced by Cisatracurium or Rocuronium |
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| Li Chunlian,Cui Wei,Yu Yonghao.Comparison of effect of Sevoflurane on Neuromuscular Blockade Induced by Cisatracurium or Rocuronium[J].Chinese Journal of Surgery of Integrated Traditional and Western Medicine,2011,17(2):165-167. |
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| Authors: | Li Chunlian Cui Wei Yu Yonghao |
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| Institution: | Li Chunlian,Cui Wei,Yu Yonghao.Department of Anesthesiology,General Hospital of Tianjin Medical University,Tianjin(300052),China |
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| Abstract: | Objective To compare the effects of sevoflurane on neuromuscular blockade induced by cisatracurium or rocureonium.Methods Two hundred and 40 patients for elective surgery were randomized to receive a single bolus dose of cisatracurium(0.15 mg/kg) or rocuronium(0.6 mg/kg).Patients were randomly assigned to one of 2 groups(n=60 each):propofol group(group P) and sevoflurane group(group S).All patients were anesthetized with midazolam,propofol and fentany.After loss of consciousness laryngeal mask was inserted.... |
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| Keywords: | cisatracurium rocuronium neuromuscular sevoflurane |
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