| 纤维细胞生长因子滴眼液治疗外伤性角膜上皮缺损的临床观察 |
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| 引用本文： | 张若英,张俊杰.纤维细胞生长因子滴眼液治疗外伤性角膜上皮缺损的临床观察[J].中国医院药学杂志,2010(4). |
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| 作者姓名： | 张若英 张俊杰 |
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| 作者单位： | 杭州钢铁集团职工医院; |
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| 摘 要： | 目的:探讨重组牛碱性成纤维细胞生长因子滴眼液(bFGF)治疗外伤性角膜上皮缺损的临床效果和安全性。方法:将2007年1月-2008年7月在我院就诊的100例(100眼)外伤性角膜上皮缺损患者随机分成治疗组50例和对照组50例,治疗组给予bFGF滴眼,qid,每次1～2滴;对照组给予玻璃酸钠滴眼液(爱丽滴眼液)点眼,qid,每次1～2滴。并根据病情给予清创缝合、抗炎及对症处理,观察滴眼后2,4d角膜上皮缺损修复情况。结果:滴眼后2d和4d,bFGF治疗组外伤性角膜上皮缺损的治愈率均明显高于对照组,经χ2检验,治疗组与对照组在滴眼后2,4d差异均有极显著性(P<0.01)。结论:bFGF能很好地促进角膜上皮再生和修复,缩短病程,是一种治疗外伤性角膜上皮缺损的有效方法。
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| 关 键 词： | 纤维细胞生长因子滴眼液 外伤性角膜上皮缺损 |
Clinical effect and safety of bFGF eye drops in the treatment of traumatic corneal epithelial defect |
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| ZHANG Ruo-ying,ZHANG Jun-jie.Clinical effect and safety of bFGF eye drops in the treatment of traumatic corneal epithelial defect[J].Chinese Journal of Hospital Pharmacy,2010(4). |
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| Authors: | ZHANG Ruo-ying ZHANG Jun-jie |
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| Institution: | ZHANG Ruo-ying,ZHANG Jun-jie(Hangzhou Steel , Iron Group Worker\'s Hospittal,Zhejiang Hangzhou 310022,China) |
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| Abstract: | OBJECTIVE To observe the clinical effect and safety of bFGF eye drops in the treatment of traumatic corneal epithelial defect.METHODS 100 cases of traumatic corneal epithelial defect from January 2007 to July 2008 in our hospital were randomly divided into treatment group and control group.The treatment group received bFGF eye drops,1 to 2 drops,4 times a day;the control group received Ellis Point of bFGF eye drops,every 1 to 2 drops,4 times a day.All patients were sutured,given anti-inflammatory and sympto... |
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| Keywords: | bFGF eye drops traumatic corneal epithelial defect |
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