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氨氯地平、非洛地平和缓释硝苯地平治疗高血压疗效比较
引用本文:黄震华,顾燕,许左隽,朱文敏. 氨氯地平、非洛地平和缓释硝苯地平治疗高血压疗效比较[J]. 中国新药与临床杂志, 2000, 19(2): 111-113
作者姓名:黄震华  顾燕  许左隽  朱文敏
作者单位:上海第二医科大学,附属第九人民医院,心血管病研究室,上海,200011
摘    要:目的:比较氨氯地平、非洛地平、缓释硝苯地平的降压疗效。方法:氨氯地平(5 mg, qd)、非洛地平(5 mg, qd)和缓释硝苯地平(30 mg, qd)分别治疗高血压53,50和49例,均连续口服用药 2 wk。结果:3药降压有效率分别为81%,76%,76%。3药尚有改善心肌缺血和心功能的作用。结论:3药降压作用均显著,具有服药方便、副作用小等优点。

关 键 词:高血压  心肌缺血  心功能试验  氨氯地平  非洛地平  硝苯地平  迟效制剂

Comparison of antihypertensive effects of amlodipine, felodipine and slow released nifedipine
HUANG Zhen-Hua,GU Yan,XU Zuo-Jun,ZHU Wen-Min. Comparison of antihypertensive effects of amlodipine, felodipine and slow released nifedipine[J]. Chinese Journal of New Drugs and Clinical Remedies, 2000, 19(2): 111-113
Authors:HUANG Zhen-Hua  GU Yan  XU Zuo-Jun  ZHU Wen-Min
Abstract:AIM: To compare the antihypertensive effects of amlodipine, felodipine and slow released nifedipine. METHODS: Amlodipine (5 mg, qd), felodipine (5 mg, qd) and slow released nifedipine (30 mg, qd) were used in the treatment of 53, 50 and 49 Patients with hypertension for 2 wk. RESULTS: The antihypertensive efficacy were 81%, 76% and 76%. All drugs had the effects of treating cardiac ischemia and improving cardiac function. CONCLUSION: All three drugs have the advantage of good effect, easy taking and less side effect.
Keywords:hypertension  myocardial ischemia  heart function tests  amlodipine  felodipine  nifedipine  delayed-action preparations
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