| 青年型帕金森病的临床特点 |
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| 引用本文： | 马凯,李勇杰. 青年型帕金森病的临床特点[J]. 首都医科大学学报, 2003, 24(2): 190-192 |
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| 作者姓名： | 马凯 李勇杰 |
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| 作者单位： | 首都医科大学宣武医院功能神经外科,北京市功能神经外科功研究所;首都医科大学宣武医院功能神经外科,北京市功能神经外科功研究所 |
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| 摘 要： | 对门诊治疗的帕金森病患者的临床资料进行调查,将青年型帕金森病与普通帕金森病进行比较,总结其临床特点。由专科医师对门诊病人进行问卷调查,应用SPSS统计软件对有关资料进行分析。结果:944例门诊病人中,青年型帕金森病组(n=86)与普通帕金森病组(n=858)比较,临床类型、家族史未见明显差异,改良H-Y分级在“关”状态未见明显差异,在“开”状态存在显著性差异。2组病人服用左旋多巴制剂后,不良反应的发生时间和发生率未见显著性差异。提示:青年型帕金森病组服药效果较好,药物不良反应2组间未见明显差异。
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| 关 键 词： | 帕金森病 左旋多巴 异动症 " 开-关" 现象 |
| 收稿时间： | 2002-02-27 |
| 修稿时间： | 2002-02-27 |
Clinical Characters of Young-Onset Parkinson's Disease |
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| Ma Kai,Li Yongjie. Clinical Characters of Young-Onset Parkinson's Disease[J]. Journal of Capital Medical University, 2003, 24(2): 190-192 |
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| Authors: | Ma Kai Li Yongjie |
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| Affiliation: | Ma Kai,Li YongjieDepartment of Functional Neurosurgery,Xuanwu Hospital,Affiliate of Capital University of Medical Sciences |
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| Abstract: | 944 patients with Parkinson' s disease were divided into two groups, 86 cases in young-onset Parkinson' s disease (YOPD) group and 858 cases in regular Parkinson' s disease (PD) group. Levodopa was used in 632 cases of PD. There were no significant differences concerning clinical types, family history, side effects of levodopa. There were no significant differences concerning modified Hoehn-Yahr (H-Y)scale during "off" state between YOPD group and PD group, while significant difference was found between YOPD group and PD group concerning modified Hoehn-Yahr (H-Y)scale during "on" state. |
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| Keywords: | Parkinson's disease,levodopa,dyskinesia," on-off" phenomena |
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