经皮椎体后凸成形术治疗老年骨质疏松性椎体压缩性骨折的疗效观察及安全性评估

目的：研究经皮椎体后凸成形术治疗老年骨质疏松性椎体压缩性骨折的疗效及安全性。方法将老年骨质疏松性椎体压缩性骨折患者纳入研究，随机分为给予经皮椎体后凸成形术的PKP组、经皮椎体成形术的PVP组，观察手术相关指标、近期疗效情况及远期疗效情况。结果 PKP组的手术时间（128.2±16.4）h、术后椎间隙高度（11.4±1.7）明显高于PVP组[（82.3±10.1）h、（8.8±1.2）]；骨水泥注入量（4.4±0.8）mL、骨水泥渗漏（6.15%）、下床活动时间（2.1±0.3）d、的腰部疼痛评分（1.5±0.3）、术后3、6、9、12月时的ODI评分（24.3±2.4、19.4±2.1、14.1±1.9、9.3±1.1）均明显低于PVP组[（7.1±1.0）mL、（18.46%）、（3.6±0.4）、（2.7±0.5）、（29.1±3.9）、（25.5±2.9）、（19.8±24）、（13.1±1.7）]。（P〈0.05）。结论经皮椎体后凸成形术能够减少骨水泥渗漏、促进临床症状缓解、改善远期机体功能，具有积极的临床价值。

Effect and safety of percutaneous kyphoplasty in treating agedness osteo-porotic vertebral body compression fracture

Objective To study the clinical effect and safety of PKP in treating agedness osteoporotic vertebral body compression fracture. Methods Agedness osteoporotic vertebral body compression fracture patients were enrolled and randomly divided into PKP group given percutaneous kyphoplasty and PVP group given percutaneous vertebroplasty. Then operation related index, short-term effect and long-term effect were observed. Results PKP group operation time （128.2 ±16.4）h, intervertebral space height （11.4±1.7）were significantlyhigher than those of PVP group[（82.3±10.1）h,（8.8±1.2）];bone cement injection volume（4.4±0.8）mL, bone cement leakage（6.15%）, ambulation time（2.1±0.3）d , waist pain score（1.5±0.3） ,Postoperative 3, 6, 9 and 12 months at the time ODI score（24.3±2.4、19.4±2.1、14.1±1.9、9.3±1.1） were significantly lower than PVP group[（7.1±1.0）mL,（18.46%）,（3.6±0.4）, （2.7±0.5）, （29.1±3.9）, （25.5±2.9）,（19.8±24）,（13.1±1.7）],（P〈0.05）. Conclusion Percutaneous kyphoplasty has positive clinical value for it can reduce bone cement leakage, promote the remission of clinical symptoms and improve long-term organism function.