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Higher vs Lower Oxygenation Strategies in Acutely Ill Adults: A Systematic Review With Meta-Analysis and Trial Sequential Analysis
Authors:Marija Barbateskovic  Olav L. Schjørring  Sara Russo Krauss  Christian S. Meyhoff  Janus C. Jakobsen  Bodil S. Rasmussen  Anders Perner  Jørn Wetterslev
Affiliation:1. Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, University of Copenhagen, Denmark;2. Centre for Research in Intensive Care, Rigshospitalet, University of Copenhagen, Denmark;3. Department of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Denmark;4. Cochrane Hepato-Biliary Group, Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, University of Copenhagen, Denmark;5. Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark;6. Department of Intensive Care, Rigshospitalet, University of Copenhagen, Denmark;7. Department of Anaesthesia and Intensive Care, Aalborg University Hospital, Denmark;8. Department of Regional Health Research, the Faculty of Health Sciences, University of Southern Denmark, Denmark;9. Department of Cardiology, Holbaek Hospital, Holbaek, Denmark;10. Department of Anaesthesia and Intensive Care, Aalborg University, Aalborg, Denmark
Abstract:
Keywords:critical care  meta-analysis  mortality  oxygen  systematic review  GRADE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0040"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Grading of Recommendations Assessment, Development and Evaluation  inconsistency statistics  RCT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  randomized clinical trial  RR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  relative risk  RRI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  relative risk increase  SAE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  serious adverse event  arterial oxygen saturation  peripheral oxygen saturation  TSA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0120"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Trial Sequential Analysis
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