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BMI Is Causally Associated With Pulmonary Artery Pressure But Not Hemodynamic Evidence of Pulmonary Vascular Remodeling
Authors:Timothy E Thayer  Rebecca T Levinson  Shi Huang  Tufik Assad  Eric Farber-Eger  Quinn S Wells  Jonathan D Mosley  Evan L Brittain
Institution:1. Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN;2. Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN;3. Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN;4. Vanderbilt Translational and Clinical Research Center, Vanderbilt University Medical Center, Nashville, TN;5. Departments of Medicine and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN
Abstract:
Keywords:echocardiogram  mendelian randomization  obesity  pulmonary hypertension  right heart catheterization  GRS"}  {"#name":"keyword"  "$":{"id":"kwrd0130"}  "$$":[{"#name":"text"  "_":"genetic risk score  GWAS"}  {"#name":"keyword"  "$":{"id":"kwrd0040"}  "$$":[{"#name":"text"  "_":"genome-wide association study  hpGRS"}  {"#name":"keyword"  "$":{"id":"kwrd0050"}  "$$":[{"#name":"text"  "_":"highly polygenic risk score  MEGA"}  {"#name":"keyword"  "$":{"id":"kwrd0060"}  "$$":[{"#name":"text"  "_":"Multi-Ethnic Global Array  PAH"}  {"#name":"keyword"  "$":{"id":"kwrd0070"}  "$$":[{"#name":"text"  "_":"pulmonary arterial hypertension  PH"}  {"#name":"keyword"  "$":{"id":"kwrd0080"}  "$$":[{"#name":"text"  "_":"pulmonary hypertension  PVH"}  {"#name":"keyword"  "$":{"id":"kwrd0090"}  "$$":[{"#name":"text"  "_":"pulmonary venous hypertension  RHC"}  {"#name":"keyword"  "$":{"id":"kwrd0100"}  "$$":[{"#name":"text"  "_":"right heart catheterization  sGRS"}  {"#name":"keyword"  "$":{"id":"kwrd0110"}  "$$":[{"#name":"text"  "_":"strict genetic risk score  sPAP"}  {"#name":"keyword"  "$":{"id":"kwrd0120"}  "$$":[{"#name":"text"  "_":"systolic pulmonary artery pressure
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