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Diarrheal Illness in the Pediatric Population: A Review of Neonatal Enteropathies and Childhood Idiopathic Inflammatory Bowel Disease |
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| Affiliation: | 1. Division of Transplant Surgery, Ann & Robert H. Lurie Children''s Hospital of Chicago, Northwestern University, Chicago, IL, USA;2. Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children''s Hospital of Chicago, Northwestern University, Chicago, IL, USA;3. Division of Gastroenterology, Hepatology & Nutrition, Ann & Robert H. Lurie Children''s Hospital of Chicago, Northwestern University, Chicago, IL, USA;4. Department of Pathology, Ann & Robert H. Lurie Children''s Hospital of Chicago, Northwestern University, Chicago, IL, USA |
| Abstract: | In the clinical context of pediatric diarrheal illness, the interpretation of endoscopic mucosal biopsies varies significantly from that in adults. This review outlines these differences by first describing a host of diarrheal illnesses that are nearly exclusive to the pediatric age group. The final portion of this article describes salient pathologic differences between adult and pediatric idiopathic inflammatory bowel disease. The goal of this review is to provide a brief description of each disease process and focus on practical aspects of diagnosis that are applicable for pathologists working in general practice settings. |
| Keywords: | Microvillous inclusion disease Tufting enteropathy Autoimmune enteropathy Hypobetalipoproteinemias Enteroendocrine cell dysgenesis Chronic granulomatous disease Immunodeficiencies |
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