COVID-19 and the cardiovascular system-current knowledge and future perspectives |
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| Authors: | Dimitrios G Chatzis Kalliopi Magounaki Ioannis Pantazopoulos Sonu Menachem Maimonides Bhaskar |
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| Affiliation: | Medical School, European University Cyprus, Nicosia 2404, Cyprus. moc.oohay@siztahcsoirtimid;Department of Internal Medicine, KAT General Hospital, Athens 14561, Greece;Department of Emergency Medicine, Faculty of Medicine, University of Thessaly, Larissa 41500, Greece;NSW Brain Clot Bank, NSW Health Pathology, Sydney, NSW 2170, Australia;Department of Neurology and Neurophysiology, Liverpool Hospital and South Western Sydney Local Health District, Sydney, NSW 2170, Australia |
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| Abstract: | The current coronavirus disease 2019 (COVID-19) pandemic has had devastating impact on populations around the world. The high mortality rates in patients with COVID-19 has been attributed to the influence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), its causative viral agent, on several physiological systems in human body, including the respiratory, cardiovascular, and neurological systems. There is emerging evidence on propensity of this virus to attack cardiovascular system. However, various pathophysiological mechanisms by which SARS-CoV-2 interacts with cardiovascular system and leads to high morbidity and mortality, including cardiovascular complications, are poorly understood. This mini review aims to provide an update on the current knowledge and perspectives on areas of future research. |
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| Keywords: | COVID-19 Angiotensin-converting enzyme 2 receptors Cardiovascular manifestations Therapies |
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