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Analysis of 49 autosomal SNPs in an Iraqi population
Institution:1. Laboratoire de Biochimie Immunologie, Faculté des Sciences, Université Mohammed V, Morocco;2. Laboratoire d''épidémiologie, Institut National d''Hygienne, Rabat, Morocco
Abstract:Forty-nine of the 52 autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex were typed in 101 unrelated Iraqis living in Denmark. No significant deviation from HWE was found in all but one of the 49 SNP systems and no significant pairwise linkage disequilibrium was observed for any SNP pair. When 18 worldwide populations were compared (including populations in Iraq, Turkey, Israel, Pakistan, India, China, Taiwan, Japan, Siberia, Algeria, Somalia, Uganda, Mozambique, Angola, Nigeria, Denmark, Portugal, Spain), a significant global FST value was obtained. All but six FST values were statistically significant when pairwise comparisons were performed between the 18 populations. The Iraqi population did not show significant difference from the population in Turkey and it grouped together with other Middle-Eastern populations when a multidimensional scaling plot was drawn based on the pairwise FST values. The combined mean match probability and the typical paternity index for trios were 8.3 × 10?20 and 259,000, respectively, for the Iraqi population.
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