| 病毒性肝炎患者血浆一氧化氮和内皮素水平及意义 |
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| 引用本文： | 郑曲波,李灼亮,罗端德,曾令兰. 病毒性肝炎患者血浆一氧化氮和内皮素水平及意义[J]. 临床肝胆病杂志, 1999, 15(2): 93-95 |
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| 作者姓名： | 郑曲波 李灼亮 罗端德 曾令兰 |
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| 作者单位： | 1. 510602,空军广州医院解放军传染病中心
2. 同济医科大学附属协和医院传染病实验室 |
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| 摘 要： | 各型病毒性肝炎及活动性肝硬化患者共２１３例，采用镉柱还原法及重氮化法检测ＮＯ＾－２／ＮＯ＾－３水平，放免法检测了ＥＴ－１水平。急性肝为，慢性活动型肝炎，肝炎肝硬化等各型肝病患者血清ＮＯ＾－２／ＮＯ＾－３及ＥＴ－１水平均有不同程度的升高，肝炎急性期ＮＯ就有明显升高，慢性肝病ＮＯ与ＥＴ随病情进展水平升高，二者水平良好的相关性。
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| 关 键 词： | 病毒性肝炎 肝炎后肝硬化 一氧化氮 内皮素 |
| 修稿时间： | 1998-04-20 |
Alterations and significance of plasma nitric oxide and endothelia in patients with viral hepatitis and liver cirrhosis |
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| Zheng Qubo,Li Zhuoliang,et al-Infections Disease Research Center of PLA,The th Hosipitalof PLA. Alterations and significance of plasma nitric oxide and endothelia in patients with viral hepatitis and liver cirrhosis[J]. Chinese Journal of Clinical Hepatology, 1999, 15(2): 93-95 |
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| Authors: | Zheng Qubo Li Zhuoliang et al-Infections Disease Research Center of PLA The th Hosipitalof PLA |
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| Affiliation: | Zheng Qubo,Li Zhuoliang,et al-Infections Disease Research Center of PLA,The 458th Hosipitalof PLA |
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| Abstract: | To study the alterations and significance of the plasmalevers of nitric oxide(NO) and endothelia(ET) in patients with viralhepatitisandlivercirrhosis-Plasmaleversof NO-2 /NO-3 and ET 1 were measured using Griessreaction and IFAin 213 cases of patients with viral hepatitisincluded acute icteric hepatitis,acute non icteric hepatitis,chronic persistent hepatits,chronic active hepatitis and liver cirrhosis-The plasmalevers of NO-2 /NO-3 were allelevated( P< 0-01)exceptforthe group of chronic persistenthepatitis-The plasma levels of ET 1 were elevated in groups of acute icteric hepatitis( P< 0-05) ,chronic active hepatitis and liver cirrhosis( P< 0-01)-And there were positive correlation be tween thelevels of NO-2 /NO-3 and ET 1- |
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| Keywords: | Viral hepatitis Liver cirrhosis Nitric oxide Endothelin |
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