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Évaluation du risque cardiovasculaire chez les patients hypertendus selon le SCORE2 et le SCORE OP dans une population d'Afrique subsaharienne
Institution:1. Service d''hématologie clinique et greffe de moelle, CHU Mohammed VI, Université Cadi Ayyad, Marrakech, Maroc;2. Service d''hématologie clinique et greffe de moelle osseuse, CHU Mohammed VI, Université Cadi Ayyad, Marrakech, Maroc;1. service de cardiologie du centre hospitalier Mohammed VI -Tanger, Morocco.;1. Department of Internal Medicine, Douala General Hospital, Cameroon;2. Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon;3. Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon;4. Department of Internal Medicine, Douala Laquintinie Hospital, Cameroon;5. Faculty of Sciences, University of Douala, Cameroon;6. Faculty of Medicine and Biomedical Sciences, University of Garoua, Cameroon;7. Faculty of Health Sciences, University of Buea, Cameroon;1. Department of Radiology, Bichat Hospital, Assistance Publique-Hôpitaux de Paris, 46 rue Henri Huchard, 75018, Paris, France;2. Department of Internal Medicine, Erasme Hospital, 808 Lennik Road, 1070, Brussels, Belgium;3. INSERM U1148, Paris, France;4. Paris University, Paris, France
Abstract:BackgroundHypertension is a major risk factor for cardiovascular events. The cardiovascular risk assessment is performed using specific algorithms, particularly SCORE2 and SCORE2-OP developed by the European Society of Cardiology.Patients and methodsProspective cohort study from February 1, 2022, to July 31, 2022, enrolling 410 hypertensive patients. Epidemiological, paraclinical, therapeutic, and follow-up data were analyzed. Cardiovascular risk stratification of patients was performed using SCORE2 and SCORE2-OP algorithms. We compared the initial and 6-month cardiovascular risks.ResultsThe mean age of the patients was 60.88 ± 12.35 years with a female predominance (sex ratio = 0.66). In addition to hypertension, dyslipidemia (45.4%) was the most frequently associated risk factor. A high proportion of patients were classified as high (48.6%) and very high (46.3%) cardiovascular risk, with a significant difference between men and women. Reassessment of cardiovascular risk after 6 months of treatment found significant differences compared with the initial cardiovascular risk (p < 0.001). The rate of patients at low to moderate cardiovascular risk (49.5%) increased substantially, whereas the proportion of patients at very high risk decreased (6.8%).ConclusionOur study conducted at Abidjan Heart Institute in a young population of patients with hypertension revealed a severe cardiovascular risk profile. Almost half of the patients are classified at very high cardiovascular risk, based on the SCORE2 and SCORE2-OP. The widespread use of these new algorithms for risk stratification should lead to more aggressive management and prevention strategies for hypertension and associated risk factors.
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