Comparison of Rehabilitation Training at Different Timepoints to Restore Shoulder Function in Patients With Breast Cancer After Lymph Node Dissection: A Randomized Controlled Trial |
| |
| Institution: | 1. Department of Rehabilitation, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China;2. Department of Traditional Chinese Medicine, China Resources & WISCO General Hospital, Wuhan, China;3. Department of Thyroid and Breast Surgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China;1. NHMRC Centre of Research Excellence in Aphasia Recovery and Rehabilitation, Melbourne, Australia;2. Discipline of Speech Pathology, School of Allied Health, Human Services and Sport, La Trobe University, Bundoora, Australia;3. School of Medical and Health Sciences, Edith Cowan University, Perth, Australia;4. Queensland Aphasia Research Centre, University of Queensland, Brisbane, Australia;5. Faculty of Health and Behavioural Sciences, School of Health and Rehabilitation Sciences, University of Queensland, Brisbane, Australia;6. Melbourne Medical School, University of Melbourne, Parkville, Australia;7. Stroke Division, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Australia;8. Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh PA;9. Geriatric Research, Education, and Clinical Center and Audiology and Speech Pathology Service, VA Pittsburgh Healthcare System, Pittsburgh PA;10. Brain Recovery and Rehabilitation Group, Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Australia;11. School of Psychological Sciences, Macquarie University, Sydney, Australia;1. Massachusetts Veterans Epidemiology and Research Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA;2. Department of Gerontology, University of Massachusetts Boston, Boston, MA;3. Medical Practice Evaluation Center and Center for Aging and Serious Illness, Mongan Institute, Department of Medicine, Massachusetts General Hospital, Boston, MA;4. Department of Clinical Research, Copenhagen University Hospital, Hvidovre, Denmark;5. Department of Clinical Medicine, University of Copenhagen, Denmark;6. New England Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Boston, MA;7. Harvard Medical School, Boston, MA;8. Boston University, Boston, MA;9. Brigham and Women''s Hospital, Boston, MA;10. Geriatrics and Extended Care, VA Boston Healthcare System, Boston, MA;11. Spaulding Rehabilitation Hospital, Boston, MA;1. Department of Occupational Therapy, Gannon University, Erie, PA;2. Department of Health Professions, Nova Southeastern University, Davie, FL;1. Department of Epidemiology and Biostatistics, Michigan State University – College of Human Medicine, Grand Rapids, MI;2. John F. Butzer Center for Research and Innovation, Mary Free Bed Rehabilitation Hospital, Grand Rapids, MI;3. Division of Rehabilitation, Michigan State University – College of Human Medicine, Grand Rapids, MI;4. Department of Biostatistics, Grand Valley State University, Grand Rapids, MI;1. Department of Rehabilitation, Hyogo College of Medicine Sasayama Medical Center, Kurooka, Tambasasayama, Japan;2. Department of Rehabilitation, Nishiyamato Rehabilitation Hospital, 3-2-2 Sasayuridai, Kanmaki, Japan;3. Department of Physical Therapy, School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima, Japan;4. Department of Physical Therapy, Faculty of Health Sciences, Kio University, Koryo, Japan;5. Department of Physical Therapy, Faculty of Rehabilitation Sciences, Nagoya Gakuin University, Nagoya, Japan;6. The First Nursing Course, Aichi Prefectural School of General Nursing, Nagoya, Japan;7. Inclusive Medical Science Research Institute, Morinomiya University of Medical Sciences, Osaka, Japan;8. Department of Physical Therapy, School of Health Sciences, Sapporo Medical University, Sapporo, Japan;9. Graduate School of Health Sciences, Kagoshima University, Kagoshima, Japan;10. Department of Physical Therapy, Kagoshima Medical Professional College, Kagoshima, Japan;11. Department of Physical Therapy, Faculty of Nursing and Rehabilitation, Konan Women''s University, Kobe, Japan;12. Rehabilitation Progress Center Incorporated, Itabashi rehabili home-visit nursing station, Tokyo, Japan;13. Kawaguchi Neurosurgery Rehabilitation Clinic, Hirakata, Japan;14. Boys & Girls, Daycare facilities for persons with severe motor and intellectual disabilities, Toyonaka, Japan;15. Faculty of Rehabilitation, Kansai Medical University, Hirakata, Japan;1. Kennedy Krieger Institute, Baltimore, MD;2. Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD;3. Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD;4. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD |
| |
| Abstract: | ObjectiveTo investigate whether advancing the initiation of rehabilitation training compared with the time recommended by the guidelines after breast cancer (BC) surgery is beneficial to the recovery of shoulder function and quality of life.DesignProspective, observational, single center, randomized controlled trial.SettingThe study was conducted between September 2018 and December 2019, with a 12-week supervised intervention and 6-week home-exercise period concluding in May 2020.ParticipantsTwo hundred BC patients received axillary lymph node dissection (N=200).InterventionsParticipants were recruited and randomly allocated into 4 groups (A, B, C, and D). Group A started range of motion (ROM) training at 7 days postoperative and progressive resistance training (PRT) at 4 weeks postoperative; group B started ROM training at 7 days postoperative and PRT at 3 weeks postoperative; group C started ROM training at 3 days postoperative and PRT at 4 weeks postoperative; and group D started ROM training at 3 days postoperative and PRT at 3 weeks postoperative.Main Outcome MeasuresThe primary outcome measure was Constant-Murley Score. Secondary outcome measures included ROM, shoulder strength, grip, European Organization Research and Treatment of Cancer breast cancer-specific quality-of-life questionnaire module (EORTC QLQ-BR23), and SF-36. Incidence of adverse reactions (drainage and pain) and complications (ecchymosis, subcutaneous hematoma, lymphedema) were also assessed.ResultsParticipants who started ROM training at 3 days postoperative obtained more benefits in mobility, shoulder function, and EORTC QLQ-BR23 score, while patients who started PRT at 3 weeks postoperative saw improvements in shoulder strength and SF-36. Incidence of adverse reactions and complications were low in all 4 groups, with no significant differences among the 4 groups.ConclusionsAdvancing ROM training initiation to 3 days postoperative or PRT to 3 weeks postoperative can better restore shoulder function after BC surgery and lead to faster quality of life improvement. |
| |
| Keywords: | Time factors |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
