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Hepatoprotective activity of Balsamodendron mukul extract against Paracetamol-induced liver toxicity in rats: In vivo pharmacological and toxicological evaluation
Affiliation:1. Department of Pharmacology, H.K.E Society''s, Matoshree Taradevi Rampure Institute of Pharmaceutical Sciences, Sedam road, 585105 Gulbarga, Karnataka, India;2. Department of Pharmacology, Shivnagar Vidya Prasarak Mandal''s, College of Pharmacy (Affiliated to Savitribai Phule Pune University), Malegaon (Bk), Baramati, 413115 Pune, Maharashtra, India;3. Department of Pharmaceutics, Dattakala Shikshan Sanstha, Dattakala College of Pharmacy (Affiliated to Savitribai Phule Pune University), Swami Chincholi, Daund, 413130 Pune, Maharashtra, India;4. Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John''s University, 8000 Utopia Parkway, 11439 Queens, NY, USA;5. Department of Pharmacognosy, PES Modern College of Pharmacy (Affiliated to Savitribai Phule Pune University), Nigdi, 411044 Pune, Maharashtra, India;1. College of Pharmacy, Fujian Key Laboratory of Chinese Materia Medica, Fujian University of Traditional Chinese Medicine, Fuzhou, 350100, China;2. NICM Health Research Institute, Western Sydney University, Westmead, NSW, 2145, Australia;1. National Poisons Centre, University of Otago, Dunedin, New Zealand;2. School of Pharmacy, University of Otago, Dunedin, New Zealand;1. Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA;2. Peter Munk Cardiac Centre and Heart and Stroke Richard Lewar Centre, University of Toronto, Toronto, Ontario, Canada;3. Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA;4. University of Ottawa Heart Institute, Ottawa, Ontario, Canada;5. St. Michael''s Hospital, University of Toronto, Toronto, Canada;6. Canadian VIGOUR Centre, University of Alberta, Edmonton, Canada;7. National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA;8. Department of Internal Medicine, Division of Cardiology, Konyang University, Seo-gu, Taejon, South Korea;9. Heart Research Center, Chonnam National University, Gwangju, South Korea;10. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA;11. Worldwide Network of Innovation in Clinical Education and Research (WNICER) Institute, New York, New York, USA;12. Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada;13. Department of Medicine, Mazankowski Alberta Heart Institute and University of Alberta, Edmonton, Alberta, Canada;1. Department of Hepatobiliary-Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China;2. Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun 130033, China;1. Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA;2. Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa, USA;1. Institut für Pharmazeutische Technologie und Biopharmazie, Technische Universität Braunschweig, Mendelssohnstraße 1, D-38106 Braunschweig, Germany;2. Zentrum für Pharmaverfahrenstechnik (PVZ), Franz-Liszt-Straße 35a, D-38106 Braunschweig, Germany
Abstract:
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  • Keywords:Hepatoprotective activity  Serum enzymes  Paracetamol induced hepatotoxicity  Silymarin  Activité hépatoprotectrice  Enzymes sériques  Hépatotoxicité induite par le paracétamol  Silymarine
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