Multicentric Primary Angiosarcoma of Bone Mimicking Metastasis on 18F-FDG PET/CT in a Patient with a History of Sigmoid Colon Cancer: a Case Report |
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Authors: | Min Young Yoo Eun Seong Lee Seok-ki Kim Seog-Yun Park Youngmee Kwon Tak Yun Tae Sung Kim |
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Institution: | .Department of Nuclear Medicine, National Cancer Center, Goyang-si, Gyeonggi-go Korea ;.Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea ;.Department of Nuclear Medicine, Chung-Ang University Hospital, Seoul, Korea ;.Department of Pathology, National Cancer Center, Goyang-si, Gyeonggi-do Korea ;.Hematologic Oncology Clinic, Center for Specific Organs Cancer, National Cancer Center, Research Institute and Hospital, Goyang, Gyeonggi-do Korea |
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Abstract: | Primary angiosarcoma of the bone (PAB) is a rare and fatal high-grade malignant vascular bone tumor. We report a rare case of multicentric PAB mimicking bone metastasis in a 59-year-old female patient with a history of sigmoid colon cancer. This patient complained of lower back and pelvic pain and presented with multiple osteolytic bone lesions on plain radiography and pelvic computed tomography. First, bone metastasis of sigmoid colon cancer was suspected. However, on the 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan, the patient presented unusual multiple hypermetabolic osteolytic bone lesions involving contiguous bones of the lower half of the body. After bone biopsy, these lesions were confirmed to be multicentric PAB. To the best of our knowledge, this is the first case report of an 18F-FDG PET/CT scan in a patient with multicentric primary bone angiosarcoma. |
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Keywords: | Primary angiosarcoma Bone 18F-FDG positron-emission tomography |
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