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| 肿节风注射液抗小鼠肝癌Hep-A-22的作用及毒性 | |
| 引用本文： | 孙文娟,李晶,兰凤英,杨世杰. 肿节风注射液抗小鼠肝癌Hep-A-22的作用及毒性[J]. 中成药, 2003, 25(4): 313-315 |
| 作者姓名： | 孙文娟 李晶 兰凤英 杨世杰 |
| 作者单位： | 1. 重庆医科大学药理教研室,重庆,400016 2. 白求恩医科大学药理教研室,河北,石家庄 3. 长春医学高等专科学校药理教研室,吉林,长春 |
| 摘 要： | 目的：研究肿节风注射液(ZJF)抗小鼠肝癌Hep—A—22的作用及毒性。方法：建立在体荷瘤小鼠肝癌Hep—A—22模型，测定ZJF的抑瘤率和体重、胸腺指数、脾指数和给药前后外周血白细胞的影响，同时研究ZJF对人肝癌Hep—A—22细胞株生长的抑制作用。结果：ZJF具有明显的抗肿瘤作用，结论：ZJF体内、外对小鼠肝癌Hep—A—22均具有抗肿瘤作用，并可增加荷瘤鼠免疫器官指数及外周血白细胞数。 |
| 关 键 词： | 肿节风注射液 小鼠肝癌Hep－A－22 抗肿瘤作用 免疫器官 毒性 |
| 文章编号： | 1001-1528(2003)04-0313-03 |
| 修稿时间： | 2002-07-18 |
Antitumor effect of Zhongjiefeng Injection on mice liver cancer Hep-A-22 and its toxicity |
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| SUN Wen juan ,LI Jing ,LAN Feng ying ,YANG Shi jie. Antitumor effect of Zhongjiefeng Injection on mice liver cancer Hep-A-22 and its toxicity[J]. Chinese Traditional Patent Medicine, 2003, 25(4): 313-315 | |
| Authors: | SUN Wen juan LI Jing LAN Feng ying YANG Shi jie |
| Affiliation: | SUN Wen juan 1,LI Jing 2,LAN Feng ying 3,YANG Shi jie 2 |
| Abstract: | Objective: To study antitumor activity of Zhongjiefeng Injection (Herba sarcandrae) on mice liver cancer Hep A 22 in vivo, in vitro and its toxic reaction in mice with Hep A 22 tumor Methods: The antitumor activity and toxicity of Zhongjiefeng Injection were determined in the mice with transplantable tumor (mice liver cancer Hep A 22), and the antitumor effect of Zhongjiefeng Injection on Hep A 22 cells in vitro were determined with MTT method. Conclusion: The experiment indicates that Zhongjiefeng Injection shows significant antitumon effect increase the indexes of immune organs and amounts of WBC. |
| Keywords: | Zhongjiefeng Injection Herba sarcandrae mice liver cancer Hep A 22 antitumoral activity immune organs toxicity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |