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转移抑制基因MTSS1在结肠癌组织中的表达及其意义
引用本文:王革芳,于观贞,王咏梅,王杰军. 转移抑制基因MTSS1在结肠癌组织中的表达及其意义[J]. 临床肿瘤学杂志, 2011, 16(1): 39-41
作者姓名:王革芳  于观贞  王咏梅  王杰军
作者单位:1 200052 解放军第八五医院肿瘤科2 200070 第二军医大学长征医院肿瘤科
摘    要:目的 探讨肿瘤转移抑制候选基因MTSS1在国人结肠癌发生发展中的作用及临床意义.方法 应用组织芯片和免疫组织化学技术检测185例结肠癌组织及其对应癌旁组织中MTSS1的表达,并分析其与临床病理学特征之间的关系.结果 MTSS1在癌旁组织和癌组织中的表达率分别为100.0%和45.9%,MTSS1缺失表达与肿瘤的分化程度...

关 键 词:组织芯片  MTSS1  结肠癌
收稿时间:2010-05-27
修稿时间:2010-07-05

Expression of MTSS1 and its clinical pathological significance in colorectal cancer
WANG Ge-fang,YU Guan-zhen,WANG Yong-mei,WANG Jie-jun. Expression of MTSS1 and its clinical pathological significance in colorectal cancer[J]. Chinese Clinical Oncology, 2011, 16(1): 39-41
Authors:WANG Ge-fang  YU Guan-zhen  WANG Yong-mei  WANG Jie-jun
Affiliation:WANG Ge-fang,YU Guan-zhen,WANG Yong-mei,WANG Jie-jun.Department of Oncology,No.85 Hospital of PLA,Shanghai 200052,China
Abstract:Objective To explore MTSS1 expression in progression of colorectal cancer,and to discuss its clinical significance.Methods One hundred and eighty-five cases of colorectal cancer and the adjacent-cancer tissues were detected by tissue microarray and immunohistochemistry for MTSS1 expression.Its correlation with the clinicopathological factors was analyzed.Results The positive rate of MTSS1 expression was 100.0% in the adjacent-cancer tissues and 45.9% in colorectal cancer tissues.There was significant correl...
Keywords:Tissue microarray  MTSS1  Colorectal cancer  
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