Adenosine-Sensitive Ventricular Tachycardia: |
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Authors: | BRUCE B. LERMAN M.D. KENNETH M. STEIN M.D. STEVEN M. MARKOWITZ M.D. |
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Affiliation: | Department of Medicine, Division of Cardiology, The New York Hospital-Cornell University Medical Center, New York, New York |
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Abstract: | Adenosine-Sensitive VT. Idiopathic ventricular tachycardia (VT) is a term that refers to tachycardia that arises from ventricles devoid of apparent structural abnormalities. This form of VT is now recognized to be related to several distinct entities and includes a reentrant form typically located in the region of the left posterior fascicle, an automatic form that may originate from either ventricle, and a form that originates from the right ventricular outflow tract. This last type can account for up to 80% of cases of idiopathic VT and with few exceptions can be further subdivided into repetitive monomorphic VT and paroxysmal stress-induced VT, Evidence has accumulated suggesting that both forms of VT are related to cAMP-mediated triggered activity. The experimental underpinnings of this conclusion as well as the clinical characteristics of this form of idiopathic VT are elucidated in this review. |
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Keywords: | ventricular tachycardia triggered activity adenosine |
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