奥扎格雷钠治疗急性脑梗死的临床观察

目的观察奥扎格雷钠治疗急性脑梗死的临床疗效。方法将66例患者随机分为两组,对照组32例采用常规治疗14天,治疗组34例在常规治疗基础上使用奥扎格雷钠14天,观察神经功能、日常生活能力变化及临床疗效。结果治疗组神经功能缺损评分低于对照组,治疗组卒中量表评分及日常生活能力量表评分均高于对照组,两组比较,各项均具有统计学意义(P<0.05);第15天及第30天两组临床疗效:治疗组总有效率分别为88.24和97.06%,显效率70.59和82.36%;对照组总有效率71.88和81.50%,显效率28.13和46.88%,两组比较,各项均有统计学意义(P<0.05)。结论奥扎格雷钠为治疗急性脑梗死较理想的药物,且安全有效。

Clinical efficacy of Ozagrel Sodium in the treatment of acute cerebral infarction

Objective To investigate the clinical efficacy of Ozagrel Sodium in the treatment of acute cerebral infarction.Methods 66 cases of acute cerebral infarction patients were randomly divided into two groups: the control group(32 cases) were treated with conventional therapy for 14 days;the Ozagrel Sodium group(34 cases) were added infusion of Ozagrel Sodium in addition to the conventional therapy for 14 days;the MESSS,ESS,and Bathel index were observed on the 15th day and 30th day.Results MESSS of OZagrel Sodium group was significantly lower than that of control group(P<0.05),but ESS and BI were higher in Ozagrel Sodium group than control group(P<0.05).The total efficacy rate in Ozagrel Sodium group on the 15th day(88.24%) and 30th day(97.06%) was significantly higher than that in control group on the 15th day(71.88%) and 30th day(81.50%)(P<0.05).Conclusion Ozagrel Sodium is effective and safe in the treatment for acute cerebral infarction.