原发性胆囊癌110例临床分析

目的分析了解原发性胆囊癌的临床特点。方法总结分析110例原发性胆囊癌患者的临床表现、影像学特点、诊断和治疗情况。结果胆囊癌患者早期诊断率为8.2%(9/110);女63例,男47例;年龄31～80岁,平均年龄57.3岁。临床表现无特异性,诊断主要依靠影像学检查。110例患者均首先行B超检查,其中57例再行CT检查,23例行MRI检查。110例患者中,57例行根治性切除术,41例行姑息性切除术。88例患者获随访,术后生存期15 d至5年11个月,中位生存期为6.5个月。结论原发性胆囊癌患者早期诊断率低,预后差,病史和影像学检查是诊断胆囊癌的重要依据。

Clinical analysis of 110 patients with primary gallbladder carcinoma

Objective To investigate the clinical characteristics of primary gallbladder carcinoma. Methods The data of clinical manifestations, image characteristics, diagnosis and treatment of 110 patients with primary gallbladder carcinoma were analyzed. Results The rate of diagnosis as early primary gallbladder carcinoma was only 8. 2% (9/110) in this series. The majority of the patients were females (63/110) with an age ranging from 31 to 80 years. Clinical manifestations were not specific, and diagnosis was made mainly on image examination. Radical resection was performed for57 patients, palliative resection for 41, the rest 12 patients failed to receive operation on reasons of distant metastasis, age or other reasons. Only 88 patients were followed with a mean survival time of 196 days ranging from 15 days to 5 years and 11 months. Conclusion The primary gallbladder carcinoma is quite difficult to diagnose at the early stage, and its prognosis is usually poor. The diagnosis is made mainly depending on the medical history and image examinations.