超声斑点追踪技术对二尖瓣置换术后左心室收缩期应变的初步评估

目的 初步探讨超声斑点追踪技术评价二尖瓣置换术(MVR)后患者左心室应变的临床价值.方法 获取30例MVR患者和30例正常人的标准心尖四腔观、二腔观和左室长轴观二维动态图像.应用二维应变技术测量左室壁各节段心肌收缩期最大纵向应变(LS)和整体纵向应变(GLS),Simpson's双平面法计算左室射血分数(LVEF),GLS与LVEF相关性行Pearson相关分析.结果 ①与正常组相应节段比较,MVR组左室壁LS均明显减低,差异有统计学意义(P<0.01).组内相同室壁各节段之间、不同室壁相应节段之间比较,差异无统计学意义(P>0.05).②MVR组GLS较正常组减低,差异有统计学意义(P<0.001),GLS与LVEF呈正相关(r=0.710,P<0.01).结论 超声斑点追踪技术能够有效定量MVR术后左室收缩期应变,评价其左室整体收缩功能;源于斑点追踪的牛眼图能够实时、准确地分析节段心肌运动.

Assessement of left ventricular systolic strain in patients with mitral valve replacement by speckle tracking echocardiography

Objective To assess left ventricular systolic strain in patients with mitral valve replacement (MVR) by speckle tracking echocardiography. Methods Two-dimensional images were acquired from the apical four-chamber view, two-chamber view and long-axis of the left ventricular view in 30 MVR patients (MVR group) and 30 healthy subjects matched by age and gender(control group), and then were analysed off line to evaluate left ventricular systolic strain. The maximum systolic longitudinal strain(LS) of myocardial segments and global longitudinal strain(GLS) were measured in apical views. Left ventricular ejection fraction(LVEF) was calculated using Simpson's method. The correlation between GLS and LVEF was analyzed using Pearson's method. Results Compared with the control group, LS of corresponding segment and GLS in MVR group decreased significantly (P < 0.01), but there were no statistical differences within MVR group(P>0.05). There was a good linear positive correlation between GLS and LVEF in patients (r = 0.710, P <0.01). Conclusions Speckle tracking eehoeardiography is available for measuring left ventricular systolic strain and estimating global systolic function in patients with MVR. Bull's-eye strain map, created by speckle tracking imaging, can achieve an accurate real-time segmental wall motion analysis.