瑞舒伐他汀对老年慢性心力衰竭患者心功能的影响

目的：观察瑞舒伐他汀对老年慢性心力衰竭（CHF）患者心功能的影响。方法：将80例老年（〉60岁）CHF患者随机分为对照组和研究组,每组40例。对照组给予常规抗心力衰竭治疗,研究组在此基础上加用瑞舒伐他汀,剂量为5mg,每晚1次口服。治疗前后,评价心功能改变,心脏多普勒超声检查和检测C-反应蛋白（CRP）水平。结果：6个月时,研究组心功能改善有效率与对照组相比差异有统计学意义（P〈0.05）;两组左室射血分数（LVEF）均升高,研究组较对照组升高明显（P〈0.05）;两组CRP水平均下降,研究组较对照组下降明显（P〈0.05）。结论：瑞舒伐他汀可以改善老年CHF患者心功能和降低CRP水平。

Effect of Rosuvastatin on Cardiac Function of Elderly Patients with Heart Failure

Objective：To observe the effect of rosuvastatin on cardiac function of elderly patients with heart failure.Method：80 elderly patients（age60） with heart failure were randomly assigned to regular treatment group （40） and rosuvastatin treatment group（40）.All of them were given either regular anti-heart failure treatment or rosuvastatin（5 mg qn） additionally.Cardiac function,echocardiography and concentration of CRP were detected before and after treatment.Result：After 6 months treatment,there was statistic difference in cardiac function improvement between two gruops（P0.05）.Left ventricular ejection fraction（LVEF） rised more significantly in rosuvastatin treatment group than regular treatment group.The CRP level of both groups were descreased, the decline in rosuvastatin treatment group was more significant（P0.05）.Conclusion：Rosuvastatin can improve cardiac function of elderly patients with heart failure and decrease the plasma CRP level.