2型糖尿病颈动脉及下肢动脉病变的相关性及危险因素分析

目的：探讨2型糖尿病颈动脉及下肢动脉病变的相关性及危险因素.方法：776例2型糖尿病患者接受颈动脉及下肢动脉彩色超声检查,依据有无动脉粥样硬化病变将患者分为两组,对两组的临床资料、生化指标与超声检查结果进行比较.结果：颈动脉与下肢动脉粥样硬化程度呈正相关,年龄、LDL-C、CHOL、糖尿病病程、超敏CRP是糖尿病颈动脉及下肢动脉粥样硬化共同的危险因素,SBP是颈动脉硬化的独立危险因素;餐后2 h血糖是下肢动脉硬化的独立危险因素.结论：颈动脉与下肢动脉粥样硬化呈等级正相关,SBP高者易发生颈动脉硬化,餐后2 h血糖高者易发生下肢动脉硬化.应多因素全面控制以防治糖尿病颈动脉及下肢动脉粥样硬化.

Type 2 Diabetic Patients with Lower Extremity Artery and Carotid Artery Disease and Risk Factors Analysis

Objective：To explore the type 2 diabetic carotid and lower extremity artery disease and its risk factors. Method：776 cases with type 2 diabetic underwent carotid and lower extremity artery color doppler ultrasound examination,on the basis of a no atherosclerotic lesions,were divided into two groups. On two groups of clinical data,biochemical and ultrasound examination results were compared. Result：Carotid and lower limb atherosclerosis was positively related to the degree of age,LDL-C,CHOL,duration of diabetes,high sensitive CRP was diabetic carotid and lower extremity atherosclerotic risk factors in common. SBP was the independent risk factor for carotid atherosclerosis. 2 h postprandial glucose was an independent risk factor for lower extremity arteriosclerosis. Conclusion：Carotid and lower limb atherosclerosis hierarchically correlated,SBP high susceptible to atherosclerosis of the carotid artery,2 h postprandial hyperglycemia tend to occur in lower limb arteriosclerosis. Prevention and treatment of diabetic carotid arteries and lower limb atherosclerosis should simultaneously multiple factors comprehensive control.