凋瘤丸致药物性肝损害

1例40岁女性患者,因乳腺增生服用凋瘤丸6g,3次/d治疗。用药5d后出现上腹部不适、恶心,随后出现呕吐、食欲不振、疲乏无力,尿色深。实验室检查：ALT926U/L,AST452U/L,TBil68.9μmol/L,DBil36.5μmol/L,IBil32.4μmol/L。诊断为药物性肝损害。停用凋瘤丸,进行保肝治疗。患者住院20d后症状消失,各项指标恢复正常。

Liver damage induced by Diaoliu pills

A 40-year-old woman took Diaoliu pills 6 g thrice daily for her hyperplasia of mammary glands. After 5 days of the treatment,the patient developed the upper abdominal discomfort and nausea,followed by vomiting,fatigue and dark urine. Laboratory tests results：ALT 926 U/L,AST 452 U/L,TBil 68.9 μmol/L,DBil 36.5 μmol/L,IBil 32.4 μmol/L. Drug-induced liver damage was diagnosed. Diaoliu pills were discontinued and liver-protective treatments were given. After 20 days of hospitalization her clinical symptoms disappeared and all laboratory indices returned to normal.