| 前列腺癌患者预后因素的Cox模型分析 |
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| 引用本文： | 赵斌,王东文,张利,张剑.前列腺癌患者预后因素的Cox模型分析[J].基层医学论坛,2008,12(19):584-586. |
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| 作者姓名： | 赵斌 王东文 张利 张剑 |
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| 作者单位： | 1. 山西医科大学,山西,太原,030001
2. 山西医科大学第一医院,山西,太原,030001 |
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| 摘 要： | 目的探讨影响前列腺癌患者预后的因素。方法将我院2000年1月-2006年12月收治的125例前列腺癌患者作为观察对象,对其预后进行电话随访,运用Cox回归模型进行单因素和多因素分析。结果多因素Cox回归模型分析显示Gleason评分（RR=2.012,P=0.006）、转移症状（RR=1.964,P=0.038）、合并症（RR=1.359,P=0.010）和全雄激素阻断（RR=0.960,P=0.023）4个因素是影响前列腺癌患者生存率的主要因素。结论Gleason评分、转移症状、合并症、全雄激素阻断是影响前列腺癌预后的主要因素,应根据这些因素选择适当的治疗方法,以提高患者的生存质量,改善患者的预后。
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| 关 键 词： | 前列腺癌 预后 Cox回归模型 |
Analysis of significant prognostic factors in prostate cancer patients by Cox regression model |
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| Zhao Bin,Wang Dongwen,Zhang Li,et al..Analysis of significant prognostic factors in prostate cancer patients by Cox regression model[J].Public Medical Forum Magazine,2008,12(19):584-586. |
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| Authors: | Zhao Bin Wang Dongwen Zhang Li |
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| Institution: | Zhao Bin1,Wang Dongwen2,Zhang Li2,et al.1 Shanxi Medical University,Tai Yuan 030001,2 Department of Urology,The First Hospital of Shanxi Medical University,Tai Yuan 030001 |
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| Abstract: | Objective To study prognostic factors in prostate cancer patients.Methods A study of prognostic factors and survival from prostate cancer was conducted,using data from all patient in the First Hospital of Shanxi Medical University diagnosed with prostate cancer during 2000-2006 and followed to 2007 Oct(n = 125).Survival was analyzed by Cox regression models.Results Multivariate analysis by Cox regression model showed that Gleason score(RR=2.012,P=0.006)and metastasis complaint (RR=1.964,P=0.038) and complication (RR=1.359,P=0.010)and maximal androgen blockade (RR=0.960,P=0.023)had significant effect on survival.Conclusion Gleason score and metastasis complaint and complication and maximal androgen blockade were significant prognostic factors in prostate cancer patients. |
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| Keywords: | Prostate cancer Prognosis Cox regression model |
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