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常规肺功能与肺胺代谢功能初步探讨
引用本文:刘长庭,朱虹.常规肺功能与肺胺代谢功能初步探讨[J].军医进修学院学报,1992,13(4):321-323.
作者姓名:刘长庭  朱虹
作者单位:军医进修学院南楼一科,军医进修学院南楼一科,军医进修学院南楼一科,军医进修学院南楼一科,军医进修学院南楼一科,军医进修学院南楼一科,军医进修学院核医学科,军医进修学院核医学科,军医进修学院核医学科,军医进修学院核医学科,军医进修学院核医学科
摘    要:本文报告了36例研究对象肺廓清~(131)I-三甲基羟基-间碘-苯二胺(~(131)I-HIPDM)结果,其中31例作了常规肺功能及动脉血气检查。结果表明不同组间肺廓清~(131)I-HIPDM速率不同,能形成一个新的肺功能障碍指数。右肺廓清~(131)I-HIPDM快相与用力肺活量(FVC)、第1秒用力呼气量(FEV_1)、功能残气量(FRC)、残气量(RV)肺总量(TLC)相关P<0.01;与最大呼气流量(PEFR)、肺活量(VC)、最大通气量(MVV)、动脉血氧分压(PaO_2)相关P<0.05。肺廓清~(131)I—HIPDM速率反映了肺功能状态,对疾病分期及早期肺功能损伤检测优于常规肺功能。

关 键 词:肺功能    代谢  动脉氧分压  碘同位素

Studies on Lung Function and Metabolic Function of the Lung Amine
Liu Changting,et al..Studies on Lung Function and Metabolic Function of the Lung Amine[J].Academic Journal of Pla Postgraduate Medical School,1992,13(4):321-323.
Authors:Liu Changting  
Abstract:In this report, the~(131) I-HIPDM metabolism in the lung was studied on the 6 normal nonsmoking subjects, 8 normal smokers, 10 nonsmoking COPD patients, 7 patients with COPD of smokers and 5 bronchial asthma of nonsmokers. 31 of them were submitted to spirome-try and arterial blood gas analysis. The results showed that the clearance curve of ~(131)I-HIPDM displayed difference in the different group. The analysis of ~(131)I-HIPDM of the lung clearance may form a new index of lung dysfunction. The lung clearance of ~(131)I-HIPDM has good corelation with FVC, FEVl, FRC, RV, TLC, PEFR, VC, MVV and Pa02. The speed of ~(131)I-HIPDM of the lung clearance reflects the condition of lung function and may be a better lung functional marker in different stages of disease and early lung function injury.
Keywords:Lung function PaO2 Amine Metabolism Iodine isotopes
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