Thromboembolic complications in children with cancer |
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| Authors: | Wiernikowski John T Athale Uma H |
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| Affiliation: | Division of Hematology/Oncology, McMaster Children's Hospital Hamilton, Ontario, Canada. |
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| Abstract: | Thrombosis is a significant problem in patients with cancer. The impact of thromboembolism in association with childhood cancer is not clearly defined. Similarly the information of prevention and management of thromboembolic events in children receiving cancer-therapy is limited. This review aims to examine current knowledge regarding the epidemiology, pathophysiology and management of thrombosis in association with cancer in children. |
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| Keywords: | ALL, acute lymphoblastic leukemia AML, Acute myeloid leukemia AT, antithrombin BFM, Berlin-Frankfurt-Munster CNS, central nervous system CT, computerized tomogram CVL, central venous line DFCI, Dana-Farber Cancer Institute DVT, deep venous thrombosis ECHO, echocardiography HIT, heparin induced thrombocytopenia INR, international normalization ratio LMWH, low molecular weight heparin LP, lumbar puncture MRI, Magnetic resonance imaging MRV, Magnetic resonance venogram MRA, Magnetic resonance arteriogram NHL, non-Hodgkin's lymphoma PARKAA, prophylactic antithrombin replacement in kids with ALL on asparaginase PE, pulmonary embolism POG, Pediatric Oncology Group PC, protein C PS, protein S RA, right atrial SVT, sinovenous thrombosis TE, thromboembolism UFH, unfractionated heparin USG, ultrasonography V/Q scan, ventilation/perfusion scan |
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