| 鼻背部Rosai-Dorfman病临床病理观察 |
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| 引用本文： | 王景关,吕翔,孟凡青,周强.鼻背部Rosai-Dorfman病临床病理观察[J].诊断病理学杂志,2007,14(5):333-335. |
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| 作者姓名： | 王景关 吕翔 孟凡青 周强 |
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| 作者单位： | 南京大学医学院附属鼓楼医院病理科,南京,210008 |
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| 摘 要： | 目的探讨结外Rosai-Dorfman病的临床病理特点及诊断、鉴别诊断要点。方法对1例鼻背部Rosai-Dorfman病的肿瘤组织进行临床病理、免疫组化分析。结果该病镜下表现为多量泡沫样组织细胞及弥漫散在的淋巴细胞和浆细胞,并可见淋巴细胞吞噬现象。组织细胞S-100和CD68( )。结论发生于鼻部的结外Rosai-Dorfman病罕见,须与鼻硬结病及Langerhans细胞组织细胞增生症等鉴别。
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| 关 键 词： | Rosai-Dorfman病 鼻背部 临床病理 |
| 文章编号： | 1007-8096（2007）05-0333-03 |
| 修稿时间： | 2007-02-05 |
Rosai-Dorfman disease of nasal dorsum:a clinicopathological observation |
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| WANG Jing-mei, LV Xiang , MENG Fan-qing,et al..Rosai-Dorfman disease of nasal dorsum:a clinicopathological observation[J].Chinese Journal of Diagnostic Pathology,2007,14(5):333-335. |
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| Authors: | WANG Jing-mei LV Xiang MENG Fan-qing |
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| Institution: | Department of Pathology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China |
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| Abstract: | Objective To explore the clinical and pathological characteristics and differential diagnosis of Rosai-Dorfman disease of nasal dorsum. Methods A case of Rosai-Dorfman disease was studied with clinical pathological analysis and immunohistochemical staining. Results The patient was male,38 years old,with a painless mass in nasal dorsum for 1 year.Microscopically,the lesion consisted of sheets of histiocytes,lymphocytes and plasma cells,and lymphocytophagocytosis was observed. Conclusion Extranodal Rosai-Dorfman disease of nasal dorsum is rare.The pathological diagnosis and differentiation include rhinoscleroma,Langerhans cell histiocytosis and others. |
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| Keywords: | Rosai-Dorfman disease Nasal dorsum Clinical pathology |
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