Plant antiviral agents |
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| Authors: | Ieven M van den Berghe D A Vlietinck A J |
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| Institution: | Department of Pharmaceutical Sciences, University of Antwerp (UIA), Belgium. |
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| Abstract: | Lycorine, one of the principal alkaloids of the Amaryllidaceae, exerts an antiviral effect on several RNA and DNA viruses. This effect on the growth pattern of different viruses has now been investigated. In the presence of lycorine, a delay in virus production and a decrease in total amount of virus were observed. This inhibitory effect is concentration dependent, it is due to a block of viral protein synthesis and not to an extracellular inactivation or inhibition of viral adsorption. |
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