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Successful Radiotherapy of Primary Malignant Peripheral Nerve Sheath Tumor of the Lung
Authors:Katsuya Yanagisawa  Kenichi Nishie  Hidekazu Takahashi  Kenji Sano  Kazuyoshi Takei  Hiroshi Yamamoto  Tomonobu Koizumi  Masayuki Hanaoka
Affiliation:1.Department of Respiratory Medicine, Iida Municipal Hospital, Japan; 2.Department of Respiratory Medicine, Nagano Municipal Hospital, Japan; 3.Department of Pathology, Iida Municipal Hospital, Japan; 4.Department of Radiation Therapy, Iida Municipal Hospital, Japan; 5.First Department of Internal Medicine, Shinshu University School of Medicine, Japan; 6.Department of Hematology and Medical Oncology, Shinshu University School of Medicine, Japan
Abstract:A 71-year-old man presented with cough and bloody sputum. Computed tomography showed a mass in the lower lobe of the left lung. Histological findings in biopsy tissue revealed a malignant peripheral nerve sheath tumor (MPNST). The patient was diagnosed with primary lung MPNST based on a systemic examination. Although initial chemotherapy treatment with doxorubicin failed to control the disease, radiotherapy considerably shrank the tumor. Primary lung MPNSTs are rare, and there is no established treatment for inoperable cases. This case suggests that radiotherapy is a treatment option for primary lung MPNST.
Keywords:radiotherapy   malignant peripheral nerve sheath tumor   sarcoma
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