| 金玄痔科熏洗散有效部位制剂的GC-MS指纹图谱研究 |
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| 引用本文： | 别文华,刘蔚,李力,周道年.金玄痔科熏洗散有效部位制剂的GC-MS指纹图谱研究[J].中国药师,2015(3):390-393. |
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| 作者姓名： | 别文华 刘蔚 李力 周道年 |
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| 作者单位： | 钟祥市人民医院 湖北钟祥 431900；;马应龙药业集团博士后工作站；;武汉市中医医院;马应龙药业集团博士后工作站； |
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| 基金项目： | 湖北省教育厅产学研合作重点项目资助 (编号：CXY2009B038)；马应龙药业集团肛肠基金资助 (编号：200808) |
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| 摘 要： | 目的:对金玄痔科熏洗散及有效部位新制剂进行GC-MS分析,建立了有效部位新制剂的GC-MS指纹图谱。方法:采用GC-MS方法对金玄痔科熏洗散及有效部位新制剂中的主要组分进行分析,并确定指纹图谱中的特征指纹信息。结果:对10个批次的有效部位新制剂进行了测定,并得到了较为理想的包含特征信息的有效部位新制剂的GC-MS指纹图谱。结论:方法重复性好,所建立的指纹图谱为金玄痔科熏洗散有效部位新制剂的质量控制提供了有效手段。
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| 关 键 词： | 金玄痔科熏洗散 有效部位 气相色谱-质谱联用指纹图谱 |
| 收稿时间： | 2014/11/11 0:00:00 |
| 修稿时间： | 2014/12/5 0:00:00 |
GC-MS Fingerprint of an Active Ingredients Group from Jinxuan Zhike Xunxi Powders |
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| Bie Wenhu,Liu Wei,Li Li and Zhou Daonian.GC-MS Fingerprint of an Active Ingredients Group from Jinxuan Zhike Xunxi Powders[J].China Pharmacist,2015(3):390-393. |
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| Authors: | Bie Wenhu Liu Wei Li Li and Zhou Daonian |
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| Institution: | Bie Wenhua;Liu Wei;Li Li;Zhou Daonian;Zhongxiang People’s Hospital;Post-doctoral Research Center of Mayinglong Pharmaceutical Group Co. ,Ltd.;Wuhan Hospital of Traditional Chinese Medicine; |
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| Abstract: | ABSTRACT Objective: To analyze Jinxuan Zhike Xunxi powders (JZX) and an active ingredients group (AIG) obtained from JZX by GC-MS, and develop a characteristic fingerprint of AIG. Methods: A gas chromatography mass spectrum (GC-MS) method was applied to analyze the main compositions in JZX and AIG, and the characteristic fingerprint information in the fingerprint spectrum was determined. Results: Totally 10 batches of AIG were detected, and a promising GC-MS fingerprint spectrum containing characteristic information for AIG was obtained. Conclusion:The developed fingerprint with good repeatability can be successfully applied in the quality control of AIG. |
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| Keywords: | Jinxuan Zhike Xunxi powders Active ingredients group GC-MS fingerprint |
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