| 吡诺克辛钠滴眼液渗透压测定 |
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| 引用本文： | 李智慧,田海燕,刘洪海,李海霞,刘维彬.吡诺克辛钠滴眼液渗透压测定[J].中国药师,2015(3):513-515. |
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| 作者姓名： | 李智慧 田海燕 刘洪海 李海霞 刘维彬 |
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| 作者单位： | 德州市食品药品检验检测中心 山东德州 253000;德州市食品药品检验检测中心 山东德州 253000;德州市食品药品检验检测中心 山东德州 253000;德州市食品药品检验检测中心 山东德州 253000;德州市食品药品检验检测中心 山东德州 253000 |
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| 摘 要： | 目的:探讨渗透压计测定吡诺克辛钠滴眼液渗透压摩尔浓度方法的可行性和准确性。方法:使用渗透压计测定吡诺克辛钠滴眼液的渗透压摩尔浓度,并对其渗透压摩尔浓度进行稳定性考察。结果:不同配方吡诺克辛钠滴眼液的渗透压摩尔浓度符合眼用制剂的要求。经过室温留样渗透压摩尔浓度没有明显变化,表明该制剂质量稳定。结论:该方法简便、快速、实用,可作为吡诺克辛钠滴眼液渗透压检测的方法。
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| 关 键 词： | 渗透压计 渗透压摩尔浓度 吡诺克辛钠滴眼液 |
| 收稿时间： | 2014/9/23 0:00:00 |
| 修稿时间： | 2014/11/17 0:00:00 |
Osmotic Pressure Measurement of Pirenoxinun Sodium Eye Drops |
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| Li Zhihui,Tian Haiyan,Liu Honghai,Li Haixia and Liu Weibin.Osmotic Pressure Measurement of Pirenoxinun Sodium Eye Drops[J].China Pharmacist,2015(3):513-515. |
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| Authors: | Li Zhihui Tian Haiyan Liu Honghai Li Haixia and Liu Weibin |
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| Institution: | Dezhou Food and Drug Inspection Center, Shangdong Dezhou 253000, China;Dezhou Food and Drug Inspection Center, Shangdong Dezhou 253000, China;Dezhou Food and Drug Inspection Center, Shangdong Dezhou 253000, China;Dezhou Food and Drug Inspection Center, Shangdong Dezhou 253000, China;Dezhou Food and Drug Inspection Center, Shangdong Dezhou 253000, China |
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| Abstract: | ABSTRACT Objective: To investigate the feasibility and accuracy of osmometer in the osmolarity measurement of pirenoxinun sodium eye drops.Methods: An osmometer was used to measure the osmolarity of pirenoxinun sodium eye drops, and the stability of the osmolality was studied. Results: The osmolarity of pirenoxinun sodium eye drops with different formula conformed to the requirement of ophthalmic preparations. The osmolality showed no significant change at the ambient temperature, indicating the stability of the preparation. Conclusion:The method is simple, rapid and practical, which can be used as the osmolarity measurement method for pirenoxinun sodium eye drops. |
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| Keywords: | Osmometer Osmolality Pirenoxinun sodium eye drops |
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