左氧氟沙星注射液对老年患者血糖代谢的影响

目的研究左氧氟沙星（可乐必妥）静脉注射治疗对老年患者血糖代谢的影响。方法对我院急诊观察室2004年7月～2006年7月收诊的年龄≥65岁、接受左氧氟沙星静脉治疗至少3d的685例老年患者进行回顾性分析。结果糖代谢异常和正常患者左氧氟沙星治疗前后空腹血糖（FPG）水平间差别无显著性意义（P=0．564）；使用不同降糖药物的患者左氧氟沙星治疗前后FPG水平间差别无显著性意义（P〉0，05）；血糖调节机制损害者左氧氟沙星治疗前后血糖水平间差别无显著性意义（P=0．098）；肿瘤患者左氧氟沙星治疗前后FPG水平间差别无显著性意义（P〉0．05）；使用激素患者左氧氟沙星治疗前后FPG水平间差别无显著性意义（P〉0，05）；肝肾功能异常者左氧氟沙星静脉治疗前后FPG水平间差别无显著性意义（P〉0．05）。结论左氧氟沙星静脉治疗对老年患者糖代谢没有临床意义上的影响。

A Retrospective to Evaluate Blood Glycometabolism in Hospitalized Elderly Patients Receiving Levofloxacin Injection

Objective To study the effect of blood glycometabolism in hospitalized patients receiving levofloxacin injection.Methods To carry out a retrospective study on 685 patients,aged over 65,who were hospitalized in emergency room in Renji hospital from 2004.7 to 2006.7,and had received levofloxacin at least 3 days.Results Before and fater treatment with levofloxacin,there was no significant difference in fasting plasma glucose(FPG)levels among normal glucose metabolism and disordered glucose metabolism patients(P=0.564),patients with different hypoglycemic agents(P>0.05),glucose metabolism patients(P=0.098),patients with brain tumors(P>0.05),patients with hormone(P>0.05),and patients with abnormal liver and kidney function(P>0.05).Conclusion Levofloxacin has no siganificant effect on dysglycemia in elderly pantients.