肾移植术后肺部感染临床分析

目的探讨肾移植术后肺部感染的临床特点及治疗方法。方法对47例肾移植术后肺部感染患者的临床资料进行回顾性分析。结果47例患者中,肺部感染发生于移植术后<6个月者36例(76.60%),6~12个月8例(17.02%),>12个月3例(6.38%);其中有10例出现急性呼吸窘迫综合征(ARDS),5例病死。细菌感染15例,真菌感染5例,巨细胞病毒感染4例,结核感染2例,混合感染21例。结论肾移植术后肺部感染多发生于术后1年内,病原体呈多样性,早期发现病原体、合理治疗、及时调整免疫治疗方案是治疗成功的关键。

Clinical analysis of pulmonary infection in kidney transplantation patients

Objective To investigate the clinical features and treatment measures of pulmonary infection in kidney transplantation patients.Methods The clinical data of 47 patients with pulmonary infection following kidney transplantation were retrospectively analysed.Results Among 47 patients,36(76.60%) and 8(17.02%) patients developed pulmonary infection within 6 months and 6-12 months respectively after kidney transplantation,and 3(6.38%) patients developed infection 12 months later;10 patients developed respiratory distress syndrome,5 of whom died;The types of pulmonary infection included bacteria(5 cases),fungi(5 cases),cytomegalovirus(4 cases),tuberculosis(2 cases) and mixed infection(21 cases).Conclusion Pulmonary infection following kidney transplantation mainly occurs within one year after transplantation,pathogens are various.The key to successful treatment is early detection of the pathogens,reasonable treatment and timely adjustment of immunosuppressive agents.