重组人类促红细胞生成素防治早产儿贫血的临床疗效

目的　探讨重组人类红细胞生成素 (rh Epo)防治早产儿贫血的疗效。方法　将 60例胎龄 <35周 ,体重 <1 70 0 g的早产儿随机分为两组。治疗组 30例 ,出生第 7d皮下注射 rh Epo 2 50 u/ kg.d,1次 / 2 d,每周 3次 ,用药共 5周 ;对照组未用 rh Epo。两组均口服维生素 E及铁剂。结果　治疗组血红蛋白、红细胞数、红细胞压积、网织红细胞均高于对照组 (P<0 .0 0 1 )。治疗组输血率与对照组比较明显减少 (P<0 .0 0 1 )。治疗组早产儿体重增加高于对照组 (P<0 .0 5)。结论　早期应用 rh Epo可防治早产儿贫血 ,减少早产儿输血率

The clinical offectiveness of recombinant erythrojpopitetin treatment to prevent anemia of prematurity

Objective Studying the effectsiveness o f recombinant erythrojpopitetin(rhEpo) treatment to prevent anemia of prematurit y infants Methods Sixty prematurity infants,fatal age<35week,born w eight<1700g were divided into control and treatment groups randomized.The treatm ent grop was given rhEpo 250u/kg.d.god.IH aften seven days of borth,total 5w.bot h groups oral VitE and Fe Results The Hb RBC HCT and Ret were higher in treatment g roup than control ( P <0 001).The rate of transfusion blood was reduced in Tr eatment group ( P <0 001);The rate of weight increase was higher in treatruen t than control ( P <0 05) Conclusions Eealy treamtnet of premature infants with rhE po can prevent anemia of prematurity and reduced rate of transfusionblood