| STAT5基因rs2272087位点多态性与哮喘相关性研究 |
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| 引用本文： | 杜娟,冯清洲,左右,刘晅,叶惠玲. STAT5基因rs2272087位点多态性与哮喘相关性研究[J]. 临床肺科杂志, 2012, 17(3): 402-404 |
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| 作者姓名： | 杜娟 冯清洲 左右 刘晅 叶惠玲 |
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| 作者单位： | 深圳市第七人民医院ICU科, 广东深圳,518081 |
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| 摘 要： |
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| 关 键 词： | 信号转导子和转录激活子5 基因 多态性 哮喘 |
Study on the correlation between the rs2272087 and rs6503694 polymorphism of STAT5 gene and asthma |
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| DU Juan,FENG Qing-Zhou,ZUO You,LIU Xuan,YE Hui-Ling. Study on the correlation between the rs2272087 and rs6503694 polymorphism of STAT5 gene and asthma[J]. Journal of Clinical Pulmonary Medicine, 2012, 17(3): 402-404 |
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| Authors: | DU Juan FENG Qing-Zhou ZUO You LIU Xuan YE Hui-Ling |
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| Affiliation: | (The Seventh People’s Hospital of Shenzhen) |
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| Abstract: | Object To investigate the correlation between rs2272087 and rs6503694 polymorphism of STAT5 gene and asthma.Methods The polymerase chain reaction PCR-SBT technique was used to determine rs2272087 polymorphism in asthma and control group.Results The genotypes AA,AG and GG of rs2272087 were 0.600,0.412 and 0.167 in asthma group,0.430,0.200 and 0.367 in control group;The frequencies of allele A and G were 0.903 and 0.344 in asthma group,0.656 and 0.970 in control group;There were significant difference in two groups(P<0.05).Conclusion The rs2272087 polymorphism of STAT5 gene may be an important candidate gene for asthma. |
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